Results 11 to 20 of about 31,937 (255)

Epidemiology of the Influenza A Virus H5N1 Subtype and Memory of Immunity to the H2N2 Subtype [PDF]

mBio, 2012
In their recent paper, Peter Palese and Taia T. Wang proposed a hypothesis to explain how an older circulating subtype of influenza A virus is replaced with a novel subtype (1).
M. Terajima, J. A. B. Babon, F. Ennis
semanticscholar   +4 more sources

Surveillance of influenza A virus subtype H5N1 in a live bird market in Yangon, Myanmar: 2017-2018.

Transboundary and Emerging Diseases, 2020
A survey of influenza A viruses (IAVs) in the Mingalar-Taung-Nyunt live bird market (MTN-LBM), Yangon, Myanmar, was conducted from December 2017 to December 2018. During the survey, 455 swab samples were collected from broilers, layers, backyard chickens
Khin Thurain, P. Mon, Chanakarn Nasamran, Kamonpan Charoenkul, Supanat Boonyapisitsopa, T. Tun, Y. San, A. M. Aye, A. Amonsin   +8 more
semanticscholar   +3 more sources

Systemic infection of avian influenza A virus H5N1 subtype in humans

Human Pathology, 2009
The viral dissemination in a patient with avian influenza A subtype H5N1 infection was retrospectively studied by the immunohistochemical localization of viral nucleoprotein antigen. The pathology was marked by diffuse alveolar damage, lymphoid depletion, and reactive hemophagocytic syndrome.
Z. Zhang, Jinxia Zhang, Kai Huang, Kang‐sheng Li, K. Yuen, Y. Guan, Honglin Chen, Wai-fu Ng   +7 more
semanticscholar   +5 more sources

Human single-chain antibodies that neutralize homologous and heterologous strains and clades of influenza a virus subtype H5N1

Antiviral Therapy, 2008
Background Human antibodies that interfere with the biological activity of haemagglutinins (HAs) of influenza viruses have high potential as an antiviral agent.
Santi Maneewatch, Jeeraphong Thanongsaksrikul, T. Songserm, K. Thueng-in, Kasem Kulkeaw, Umaporn Thathaisong, P. Srimanote, P. Tongtawe, P. Tapchaisri, W. Chaicumpa   +9 more
semanticscholar   +3 more sources

Isocyanides as Influenza A Virus Subtype H5N1 Wild‐Type M2 Channel Inhibitors

ChemMedChem, 2015
AbstractBasic bulky amines such as amantadine are well‐characterized M2 channel blockers, useful for treating influenza. Herein we report our surprising findings that charge‐neutral, bulky isocyanides exhibit activities similar to—or even higher than—that of amantadine.
Shuwen Wu, Jing Huang, S. Gazzarrini, Siying He, Li-hua Chen, Jun Li, Li-Hao Xing, Chufang Li, Ling Chen, Constantinos G. Neochoritis, George P. Liao, Hai-Bing Zhou, A. Dömling, A. Moroni, Wei Wang   +14 more
semanticscholar   +4 more sources

Evolution of H5N1 Cross-Species Transmission: Adaptive Mutations Driving Avian-to-Human Infection. [PDF]

Adv Genet (Hoboken)
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Man W, Du L, Liu Y, Pang Z, Zhu H, Hong B, Xu Z, Fan H.   +7 more
europepmc   +2 more sources

Detection of Two High Pathogenicity Avian Influenza Virus (HPAIV) Subtypes, H5N1 and H5N5, in a Mass Mortality Event in Wild Seabirds and Co-Location With Dead Seals. [PDF]

Transbound Emerg Dis
H5Nx Clade 2.3.4.4b high pathogenicity avian influenza viruses (HPAIVs) have been detected repeatedly in Great Britain (GB) since autumn 2020, with H5N1 dominating detections but with low level detection of H5N5 during 2025. Globally, these viruses have caused mass mortalities in captive and wild avian and mammalian populations, including terrestrial ...
Falchieri M, Bentley E, Coombes HA, Mollett BC, Terrey J, Holland S, Stubbings E, Mcginn N, Cooper J, Ahmad S, Lewis J, Clifton B, Collinson N, Aegerter J, Venkatesh D, Russell DJF, James J, Reid SM, Banyard AC.   +18 more
europepmc   +2 more sources

Massive mobilization of dendritic cells during influenza A virus subtype H5N1 infection of nonhuman primates. [PDF]

The Journal of Infectious Diseases, 2014
Highly pathogenic avian influenza virus infection is characterized by a marked inflammatory response, but the impact of infection on dendritic cells (DCs) is unknown. We show that influenza A virus subtype H5N1 infection rapidly and profoundly impacts DCs in cynomolgus macaques, increasing the number of blood myeloid and plasmacytoid DCs by 16- and 60 ...
A. Soloff, Stephanie J. Bissel, B. F. Junecko, B. Giles, T. Reinhart, T. Ross, S. Barratt-Boyes   +6 more
semanticscholar   +3 more sources

Evidence of High Pathogenic Avian Influenza H5N1 Clade 2.3.4.4b Among Poultry in Ghana From 2021 to 2022. [PDF]

Vet Med Sci
Ghana experienced outbreaks of highly pathogenic avian influenza A H5N1 among poultry from 2021 to 2022. Analysing poultry, pigs, and environmental samples showed H5N1 prevalence of 2.36% (63/2640) among poultry only. The clade 2.3.4.4b virus showed mammalian adaptive motifs in haemagglutinin, emphasising the need for ongoing genomic surveillance among
Nyarko SO, Asante IA, Sarpong GM, Boatemaa L, Kwasah L, Awuku-Larbi Y, Magnusen V, Wutsika J, Ago S, Amenuvor EAA, Adusei-Poku M, Ntim NAA, Wordui J, Sekyi-Yorke AN, Takyi C, Nyarko JA, Quarcoo JA, Doku I, Tackie RA, Odoom T, Danso F, Nyarko EO, Asiedu W, Mingle DL, Attram N, Cameron-Paintsil S, Terrel S, Miranda H, Ampofo WK.   +28 more
europepmc   +2 more sources

Avian Influenza Virus A Subtype H5N1

UMI Medical Journal, 2023
Latar Belakang: Avian influenza adalah infeksi virus menular yang menyerang unggas, hewan, dan manusia di seluruh dunia. Sebagian besar infeksi pada manusia disebabkan oleh virus influenza tipe A dan B, sedangkan unggas hanya terinfeksi oleh influenza tipe A. Isi: Masa inkubasi umumnya 2 sampai 7 hari, tapi bisa selama 8 sampai 9 hari.
Erza Anugrah, M. Almutaali
openaire   +1 more source