Results 81 to 90 of about 282,997 (350)

Influenza virus circulation and vaccine effectiveness during June 2021–May 2023 in Thailand

Vaccine: X
Thai Ministry of Public Health recommends influenza vaccination for certain risk groups. We evaluated 2023 Southern Hemisphere influenza vaccine effectiveness against medically attended influenza using surveillance data from nine Thai hospitals and a ...
Kriengkrai Prasert, Prabda Praphasiri, Sutthichai Nakphook, Darunee Ditsungnoen, Patranuch Sapchookul, Kanlaya Sornwong, Suriya Naosri, Pilailuk Akkapaiboon Okada, Piyarat Suntarattiwong, Tawee Chotpitayasunondh, Martha P. Montgomery, William W. Davis, Chakrarat Pittayawonganon   +12 more
doaj   +1 more source

Universal influenza vaccines: from viruses to nanoparticles

Expert Review of Vaccines, 2018
Introduction: The current seasonal influenza vaccine confers only limited protection due to waning antibodies or the antigenic shift and drift of major influenza surface antigens. A universal influenza vaccine which induces broad cross-protection against
Ye Wang, Lei Deng, Sang-Moo Kang, Bao-Zhong Wang   +3 more
doaj   +1 more source

Adjuvanted influenza vaccines

Expert Review of Vaccines, 2013
Influenza is one of the most common causes of human morbidity and mortality that is preventable by vaccination. Immunization with available vaccines provides incomplete protection against illness caused by influenza virus, especially in high-risk groups such as the elderly and young children.
Orli, Even-Or, Sarit, Samira, Ronald, Ellis, Eli, Kedar, Yechezkel, Barenholz   +4 more
openaire   +2 more sources

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

The drivers of influenza vaccination in adults: Insights from a national Australian survey

Vaccine: X
Influenza vaccination coverage is suboptimal in the Australian adult population. While coverage data is used to monitor uptake, at present, there is no systematic data collection on the behavioural and social drivers of vaccination.
Maria Christou-Ergos, Majdi M. Sabahelzain, Maryke Steffens, Jessica Kaufman, Katarzyna T. Bolsewicz, Margie Danchin, Julie Leask   +6 more
doaj   +1 more source

A Review of the 2016-2017 Flu Season: Guidelines, Costs, and Barriers

Online Journal of Rural Nursing and Health Care, 2017
In the United States (US), about 50,000 influenza-related deaths occur annually (Centers for Medicaid and Medicare Services [CMS], 2014).  The most important preventive measure for the influenza virus is for people to obtain the influenza vaccine (Varsha
Simone Chinnis, James Sterrett, Richetta Deas, Whitney Smith, Ruth Conner   +4 more
doaj   +1 more source

Risk of Guillain-Barré syndrome after 2010–2011 influenza vaccination [PDF]

, 2013
Influenza vaccination has been implicated in Guillain Barré Syndrome (GBS) although the evidence for this link is controversial. A case–control study was conducted between October 2010 and May 2011 in seven Italian Regions to explore the relation between
Beghi, E, Benedetti, M D, Chiò, A, D'Alessandro, R, Filippini, G, Galeotti, F, Granieri, E, Itang, study group., Logroscino, G, Massari, M, Pugliatti, M, Raschetti, R, Santuccio, C   +12 more
core   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Surveillance and vaccine effectiveness of an influenza epidemic predominated by vaccine-mismatched influenza B/Yamagata-lineage viruses in Taiwan, 2011-12 season.

PLoS ONE, 2013
IntroductionThe 2011-12 trivalent influenza vaccine contains a strain of influenza B/Victoria-lineage viruses. Despite free provision of influenza vaccine among target populations, an epidemic predominated by influenza B/Yamagata-lineage viruses occurred
Yi-Chun Lo, Jen-Hsiang Chuang, Hung-Wei Kuo, Wan-Ting Huang, Yu-Fen Hsu, Ming-Tsan Liu, Chang-Hsun Chen, Hui-Hsun Huang, Chi-Hsi Chang, Jih-Haw Chou, Feng-Yee Chang, Tzou-Yien Lin, Wen-Ta Chiu   +12 more
doaj   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source