Results 101 to 110 of about 968,734 (398)

Roadblocks to translational challenges on viral pathogenesis. [PDF]

, 2013
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven, Drosten, Christian, Picker, Louis, Subbarao, Kanta, Suzich, Joann   +4 more
core   +1 more source

Influenza vaccination in the elderly [PDF]

Human Vaccines & Immunotherapeutics, 2017
Seasonal influenza is a prevalent and serious annual illness resulting in widespread morbidity and economic disruption throughout the population; the elderly and immunocompromised are particularly vulnerable to serious sequelae and mortality. The changing demographics worldwide to an aging society have important implications for public health policy ...
Jan Smetana, Roman Chlibek, Jana Shaw, Miroslav Splino, Roman Prymula   +4 more
openaire   +4 more sources

The Hajj 2019 Vaccine Requirements and Possible New Challenges [PDF]

, 2019
Each year millions of pilgrims perform the annual Hajj from more than 180 countries around the world. This is one of the largest mass gathering events and may result in the occurrence and spread of infectious diseases.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Relative effectiveness of cell-cultured and egg-based influenza vaccines among the U.S. elderly, 2017-18.

Journal of Infectious Diseases, 2019
Background The low influenza vaccine effectiveness (VE) observed during the A(H3N2)-dominated 2017-18 season may be due to vaccine virus adaptation to growth in eggs.
H. Izurieta, Y. Chillarige, J. Kelman, Yuqin Wei, Yun Lu, Wenjie Xu, Michael Lu, D. Pratt, Steve Chu, M. Wernecke, T. MaCurdy, R. Forshee   +11 more
semanticscholar   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

An mRNA vaccine candidate encoding cholera toxin subunit B and conserved antigens of influenza viruses confers cross-protection against influenza a viruses in adult and aged mice

Human Vaccines & Immunotherapeutics
Currently, vaccination with influenza vaccines is still an effective strategy to prevent infection by seasonal influenza virus. However, seasonal influenza vaccines frequently fail to induce effective immune protection against rapidly changing seasonal ...
Liang Xu, Zhihao Yu, Yifan Xu, Qin Wang, Guiqin Wang, Benchi Li, Qian Weng, Yongxiang Yi, Junwei Li   +8 more
doaj   +1 more source

Bacterially produced recombinant influenza vaccines based on virus-like particles. [PDF]

PLoS ONE, 2013
Although current influenza vaccines are effective in general, there is an urgent need for the development of new technologies to improve vaccine production timelines, capacities and immunogenicity.
Andrea Jegerlehner, Franziska Zabel, Alice Langer, Klaus Dietmeier, Gary T Jennings, Philippe Saudan, Martin F Bachmann   +6 more
doaj   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source

A Comparative Analysis of Influenza Vaccination Programs [PDF]

, 2006
The threat of avian influenza and the 2004-2005 influenza vaccine supply shortage in the United States has sparked a debate about optimal vaccination strategies to reduce the burden of morbidity and mortality caused by the influenza virus.
Babak Pourbohloul, Brandriss, Bryan Grenfell, Cauchemez, Cauchemez, Dauer, Dezso, Ferguson, Fox, Frost, Glezen, Govaert, Grais, Harper, Hethcote, Jennings, Lauren Ancel Meyers, Longini, Longini, Longini, Luk, Meyers, Meyers, Meyers, Mills, Monto, Newman, Noble, Olsen, Pastor-Satorras, Patel, Paul, Pourbohloul, Reichart, Shweta Bansal, Taber, Thompson, Thompson, Woolhouse   +38 more
core   +4 more sources

Influenza vaccine: a travelers’ vaccine?

Expert Review of Vaccines, 2008
Seasonal influenza affects 5-15% of the world's population annually and is considered to be the second most frequent vaccine-preventable infection in travelers. Despite increasing travel volume worldwide, guidelines on influenza vaccination for international travel are scarce.
Marti, F, Steffen, Robert, Mütsch, Margot   +2 more
openaire   +4 more sources