A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [PDF]
, 2014 Strategies to optimize responses to seasonal influenza vaccination in older adults include the use of adjuvants, higher antigen doses, and intradermal delivery.
Castellino, Flora +9 more
core +1 more source
Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
, 2014 Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow +30 more
core +3 more sources
Projected impact of a plant-derived vaccine on the burden of seasonal influenza in Canada
Human Vaccines & Immunotherapeutics, 2021 Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada.
Lauren Ramjee +7 more
doaj +1 more source
Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity
Vaccines, 2021 Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li +3 more
doaj +1 more source
Impact of communicative and informative strategies on influenza vaccination adherence and absenteeism from work of health care professionals working at the university hospital of palermo, Italy: A quasi-experimental field trial on twelve influenza seasons [PDF]
, 2019 Every year, about 20% of health care workers (HCWs) acquire influenza, continuing to work and encouraging virus spreading. Influenza vaccination coverage rates and absenteeism from work among HCWs of the University Hospital (UH) of Palermo were analyzed ...
Bono S. +8 more
core +1 more source
Vaccines, 2018 Vaccination against influenza is the most effective approach for reducing influenza morbidity and mortality. However, influenza vaccines are unique among all licensed vaccines as they are updated and administered annually to antigenically match the ...
Surender Khurana
doaj +1 more source
A review of the changes to the licensing of influenza vaccines in Europe [PDF]
, 2015 In 2014, the European Committee for Medicinal Products for Human Use (CHMP) published a draft regulatory guideline for the evaluation of influenza vaccines.
Voordouw, A.C.G. (Bettie) +1 more
core +2 more sources
Cell culture-derived flu vaccine: Present and future
Human Vaccines & Immunotherapeutics, 2018 The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV ...
Alberto Pérez Rubio, Jose María Eiros
doaj +1 more source
Protective efficacy of a broadly cross-reactive swine influenza DNA vaccine encoding M2e, cytotoxic T lymphocyte epitope and consensus H3 hemagglutinin [PDF]
, 2012 BACKGROUND: Pigs have been implicated as mixing reservoir for the generation of new pandemic influenza strains, control of swine influenza has both veterinary and public health significance.
Bin Wang +5 more
core +1 more source
Virus-Vectored Influenza Virus Vaccines
Viruses, 2014 Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide.
Ralph A. Tripp, S. Mark Tompkins
doaj +1 more source