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Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity

open access: yesVaccines, 2021
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li   +3 more
doaj   +1 more source

Projected impact of a plant-derived vaccine on the burden of seasonal influenza in Canada

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada.
Lauren Ramjee   +7 more
doaj   +1 more source

Adjuvanted influenza vaccines [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2012
The search for adjuvants has been stimulated by the need to ensure greater protection against influenza among subjects who show a reduced immune response to conventional influenza vaccines. Aluminum salts have long been used but are not considered satisfactory.
N. Principi, S. Esposito
openaire   +5 more sources

Immunogenicity and tolerability of an MF59-adjuvanted, egg-derived, A/H1N1 pandemic influenza vaccine in children 6-35 months of age [PDF]

open access: yes, 2014
Background: Vaccines against pandemic A/H1N1 influenza should provide protective immunity in children, because they are at greater risk of disease than adults.
Abarca, Katia   +9 more
core   +2 more sources

Cell culture-derived flu vaccine: Present and future

open access: yesHuman Vaccines & Immunotherapeutics, 2018
The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV ...
Alberto Pérez Rubio, Jose María Eiros
doaj   +1 more source

Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy [PDF]

open access: yes, 2018
Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection.
Alicino C.   +9 more
core   +1 more source

Virus-Vectored Influenza Virus Vaccines

open access: yesViruses, 2014
Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide.
Ralph A. Tripp, S. Mark Tompkins
doaj   +1 more source

Protective efficacy of a broadly cross-reactive swine influenza DNA vaccine encoding M2e, cytotoxic T lymphocyte epitope and consensus H3 hemagglutinin [PDF]

open access: yes, 2012
BACKGROUND: Pigs have been implicated as mixing reservoir for the generation of new pandemic influenza strains, control of swine influenza has both veterinary and public health significance.
Bin Wang   +5 more
core   +1 more source

Impact of communicative and informative strategies on influenza vaccination adherence and absenteeism from work of health care professionals working at the university hospital of palermo, Italy: A quasi-experimental field trial on twelve influenza seasons [PDF]

open access: yes, 2019
Every year, about 20% of health care workers (HCWs) acquire influenza, continuing to work and encouraging virus spreading. Influenza vaccination coverage rates and absenteeism from work among HCWs of the University Hospital (UH) of Palermo were analyzed ...
Bono S.   +8 more
core   +1 more source

A review of the changes to the licensing of influenza vaccines in Europe [PDF]

open access: yes, 2015
In 2014, the European Committee for Medicinal Products for Human Use (CHMP) published a draft regulatory guideline for the evaluation of influenza vaccines.
Voordouw, A.C.G. (Bettie)   +1 more
core   +2 more sources

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