Results 31 to 40 of about 201,288 (355)

Role of vaccines in preventing influenza in healthy children [PDF]

, 2021
The role of an influenza vaccine is to minimise illness and death. Vaccines provide good protection against influenza strains and significantly reduce time off work. However, the recommendation for use depends on the efficacy, effectiveness and safety of
Cooper, S, Sambala, E Z, Schmidt, B-M, Walaza, S, Wiysonge, C S   +4 more
core   +2 more sources

INDUCTION OF SECONDARY BACTERIAL PNEUMONIA IN MICE INFECTED WITH PANDEMIC AND LABORATORY STRAINS OF THE H1N1 INFLUENZA VIRUS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. In this study we developed and characterized a mouse model of secondary S. aureus and S. pneumoniae pneumonia following influenza virus infection with H1N1 pandemic and laboratory strains and their reassortment. Materials and methods.
I. A. Leneva, A. Yu. Egorov, I. N. Falynskova, N. R. Маkhmudоvа, N. P. Kartashova, E. A. Glubokova, N. O. Vartanova, A. V. Poddubikov   +7 more
doaj   +1 more source

MF59-adjuvanted influenza vaccine (FLUAD®) elicits higher immune responses than a non-adjuvanted influenza vaccine (Fluzone®): A randomized, multicenter, Phase III pediatric trial in Mexico

Human Vaccines & Immunotherapeutics, 2018
The poor immune response elicited by trivalent influenza vaccines (TIVs) in children can be enhanced by the addition of adjuvants. This observer-blind, randomized Phase III trial assessed the immunogenicity and safety of the MF59-adjuvanted trivalent ...
Aurelio Cruz-Valdez, Gabriel Valdez-Zapata, Sanjay S. Patel, Flavia V. Castelli, Marcia G. Garcia, Wim T. Jansen, Ashwani Kumar Arora, Esther Heijnen   +7 more
doaj   +1 more source

Prediction of Influenza B Vaccine Effectiveness from Sequence Data [PDF]

Protein Engineering, Design & Selection 29 (2016) 309-315, 2016
Influenza is a contagious respiratory illness that causes significant human morbidity and mortality, affecting 5-15% of the population in a typical epidemic season. Human influenza epidemics are caused by types A and B, with roughly 25% of human cases due to influenza B.
arxiv   +1 more source

Influenza Virus and Vaccination [PDF]

Pathogens, 2020
Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen.
Aitor Nogales, Marta L. DeDiego
openaire   +5 more sources

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

New Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini, I. Magouras, C. Chapuis‐Taillard, O. Clerc, E. Masserey, G. Peduto, O. Péter, S. Schaerrer, G. Schuepbach, G. Greub   +9 more
wiley   +1 more source

A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future [PDF]

, 2021
Improved influenza vaccines are urgently needed to reduce the burden of seasonal influenza and to ensure a rapid and effective public-health response to future influenza pandemics.
Ampofo, William, Barclay, Wendy, Bresee, Joseph S., Cavaleri, Marco, Cohen, Cheryl, Cowling, Benjamin, Cox, Rebecca Jane, Friede, Martin H., Gellin, Bruce G., Golding, Josephine P., Gust, Ian, Hart, Peter J., Innis, Bruce, Kang, Gagandeep, Katz, Jacqueline M., Kraigsley, Alison M., Krammer, Florian, Mehr, Angela J., Moen, Ann, Moore, Kristine A., Osterholm, Michael T., Ostrowsky, Julia T., Pitisuttithum, Punnee, Post, Diane, Rudenko, Larisa, Siqueira, Marilda M., Weir, Jerry P., Weller, Charlotte L.   +27 more
core   +1 more source

Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti‐spike neutralizing IgG to SARS‐CoV‐2 variants, but preserved antigen‐specific T cell responses

American Journal of Hematology, Volume 98, Issue 1, Page 131-139, January 2023., 2023
Abstract Patients with indolent lymphoma undertaking recurrent or continuous B cell suppression are at risk of severe COVID‐19. Patients and healthy controls (HC; N = 13) received two doses of BNT162b2: follicular lymphoma (FL; N = 35) who were treatment naïve (TN; N = 11) or received immunochemotherapy (ICT; N = 23) and Waldenström's macroglobulinemia
Brendan Beaton, Sarah C. Sasson, Katherine Rankin, Juliette Raedemaeker, Alexander Wong, Priyanka Hastak, Chansavath Phetsouphanh, Andrew Warden, Vera Klemm, C. Mee Ling Munier, Alexandra Carey Hoppe, Fiona Tea, Aleha Pillay, Alberto Ospina Stella, Anupriya Aggarwal, Orly Lavee, Ian D. Caterson, Stuart Turville, Anthony D. Kelleher, Fabienne Brilot, Judith Trotman   +20 more
wiley   +1 more source

Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses

Frontiers in Immunology, 2019
Dendritic cells (DCs) facilitate cross talk between the innate and adaptive immune system. They sense and phagocytose invading pathogens, and are not only capable of activating naïve T cells, but can also determine the polarization of T cell responses ...
Demo Yemane Tesfaye, Demo Yemane Tesfaye, Arnar Gudjonsson, Arnar Gudjonsson, Bjarne Bogen, Bjarne Bogen, Bjarne Bogen, Even Fossum, Even Fossum   +8 more
doaj   +1 more source

Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment [PDF]

, 2014
There is an urgent need for rapid methods to develop vaccines in response to emerging viral pathogens. Whole inactivated virus (WIV) vaccines represent an ideal strategy for this purpose; however, a universal method for producing safe and immunogenic ...
Achilefu, Samuel, Chen, Alexander, Donthi, Nisha, Hsieh, Wen-Han, Hung, Chien-Fu, Knoff, Jayne, La, Victor, Li, Yen-Der, Tsen, Kong-Thon, Tsen, Shaw-Wei David, Wu, Tzyy-Choou   +10 more
core   +2 more sources