Results 31 to 40 of about 211,619 (334)

Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity

open access: yesVaccines, 2021
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li   +3 more
doaj   +1 more source

The post-2009 influenza pandemic era : time to revisit antibody immunodominance [PDF]

open access: yes, 2018
The current inactivated influenza vaccines rely on the induction of neutralizing antibodies against the head domain of the viral hemagglutinin (HA). The HA head contains five immunodominant antigenic sites, all of which are subject to antigenic drift ...
Caton   +6 more
core   +1 more source

Development and Regulation of Novel Influenza Virus Vaccines: A United States Young Scientist Perspective

open access: yesVaccines, 2018
Vaccination against influenza is the most effective approach for reducing influenza morbidity and mortality. However, influenza vaccines are unique among all licensed vaccines as they are updated and administered annually to antigenically match the ...
Surender Khurana
doaj   +1 more source

Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]

open access: yes, 2017
The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin   +8 more
core   +2 more sources

Cell culture-derived flu vaccine: Present and future

open access: yesHuman Vaccines & Immunotherapeutics, 2018
The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV ...
Alberto Pérez Rubio, Jose María Eiros
doaj   +1 more source

Projected impact of a plant-derived vaccine on the burden of seasonal influenza in Canada

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada.
Lauren Ramjee   +7 more
doaj   +1 more source

Virus-Vectored Influenza Virus Vaccines

open access: yesViruses, 2014
Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide.
Ralph A. Tripp, S. Mark Tompkins
doaj   +1 more source

Construction and characterization of H5N1-recombinant fowlpox viruses co-expressing host cytokines [PDF]

open access: yes, 2011
Possessing a large double stranded DNA genome up to 300 kb, fowlpox virus (FWPV) has been developed to express avian influenza virus (AIV) antigens since the late 1980s. A more advanced approach would be to coexpress host cytokines from such recombinants.
Abdul Razak, Mariatulqabtiah   +1 more
core   +1 more source

Relapse of polymyalgia rheumatica following adjuvanted influenza vaccine: A case-based review [PDF]

open access: yes, 2020
Polymyalgia rheumatica (PMR) is the most common inflammatory rheumatological condition affecting individuals aged >50 years. There have been rare reports of PMR and other vasculitides developing within 3 months of influenza vaccination.
Bassendine, Margaret F., Bridge, Simon
core   +1 more source

Adjuvanted influenza vaccines [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2012
The search for adjuvants has been stimulated by the need to ensure greater protection against influenza among subjects who show a reduced immune response to conventional influenza vaccines. Aluminum salts have long been used but are not considered satisfactory.
N. Principi   +1 more
openaire   +7 more sources

Home - About - Disclaimer - Privacy