Results 81 to 90 of about 17,455,412 (293)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

On ethically aligned information fusion for defence and security systems

, 2022
8 S.Research on Information Fusion does not consider whether and with what capabilities defense and security systems should be developed. Nor does it have to assess the ethical dimension of their use.
Koch, W.
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Approaching Semantically-Mediated Acoustic Data Fusion [PDF]

, 2007
Our primary hypothesis is that it should be possible to enrich data fusion by semantic processing, with wide potential application. In order to achieve our aim we need to represent the semantic data and enable reasoning about it in a framework that can ...
Damarla, Raju, Mark S. Nixon, Shadbolt, Nigel R, Damarla, T. Raju, Nixon, Mark S., Guo, Baofeng, Shadbolt, Nigel, T. Raju Damarla, Wang, Yi, Yi Wang, Smart, Paul, Baofeng, Guo, Nigel Shadbolt, Nixon, Mark S, Baofeng Guo, Paul Smart, Smart, Paul R, Yi, Wang   +17 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Opportunistic information fusion: A new paradigm for next generation networked sensing systems

, 2005
Traditionally, Information Fusion systems assume that the information is gathered from known sensors over proprietary communication networks and fuse using fixed rules of information fusion and designated computing and communication resources.
Gulrez, T, T. Gulrez, Challa, S, S. Challa, Paranesha, TN, Chaczko, Z, Z. Chaczko, T.N. Paranesha   +7 more
core   +1 more source

The IFD03 information fusion demonstrator

, 2004
The paper discusses a recently developed demonstrator system where new ideas in tactical information fusion may be tested and demonstrated. The main services of the demonstrator are discussed, and essential experience from the use and development of the ...
Ahlberg, Simon, Lindström, Björn, Neider, Göran, Hörling, Pontus, Svenson, Pontus, Sidenbladh, Hedvig, Jöred, Karsten, Schubert, Johan, Unden, Katarina, Mårtenson, Christian, Svensson, Per, Walter, Johan   +11 more
core   +1 more source

A Lightweight Feature Optimizing Network for Ship Detection in SAR Image

IEEE Access, 2019
Deep learning-based methods have achieved great success in target detection tasks of computer vision, but when it comes to Synthetic Aperture Radar (SAR) image ship detection, some new challenges appear because of the wide swath of images, diverse ...
Xiaohan Zhang, Haipeng Wang, Congan Xu, Yafei Lv, Chunlong Fu, Huachao Xiao, You He   +6 more
doaj   +1 more source