Results 81 to 90 of about 569,332 (261)

A Lightweight Feature Optimizing Network for Ship Detection in SAR Image

IEEE Access, 2019
Deep learning-based methods have achieved great success in target detection tasks of computer vision, but when it comes to Synthetic Aperture Radar (SAR) image ship detection, some new challenges appear because of the wide swath of images, diverse ...
Xiaohan Zhang, Haipeng Wang, Congan Xu, Yafei Lv, Chunlong Fu, Huachao Xiao, You He   +6 more
doaj   +1 more source

Information fusion in taxonomic descriptions [PDF]

Proceedings of the 2013 international workshop on Mining unstructured big data using natural language processing, 2013
Providing a single access point to an information system from multiple documents is helpful for biodiversity researchers as it is true in many fields. It not only saves the time for going back and forth from different sources but also provides the opportunity to generate new information out of the complementary information in different sources and ...
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Small target detection of floating objects in river channels based on improved YOLOv7

Scientific Reports
Computer vision-aided small target detection in moving streams, such as rivers/ roads, requires a fast-converging outcome as the frame requirements are high.
Weifeng Yang, Bing Zhang, Su Guo, Kebin Gao, Jianwei Ying, Jun Zheng, Chao Li, Jun Li, Weigang Xu, Qi Chen, Jun Cao, Youxiang Zuo, Yu Chen, Wenjie Wang   +13 more
doaj   +1 more source

Node Deployment Algorithm for Underwater Sensor Networks Based on Connected Dominating Set

Sensors, 2016
Existing node deployment algorithms for underwater sensor networks are nearly unable to improve the network coverage rate under the premise of ensuring the full network connectivity and do not optimize the communication and move energy consumption during
Peng Jiang, Jun Liu, Feng Wu, Jianzhong Wang, Anke Xue   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source