Results 191 to 200 of about 169,052 (301)

Dentate gyrus network regulation by somatostatin- and parvalbumin-expressing interneurons differentially impacts spatial memory processing. [PDF]

iScience
Raven F, Vankampen AA, He A, Aton SJ.
europepmc   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Pharmacokinetics and Safety of Selumetinib Granule Formulation in Children With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas (SPRINKLE; phase I/II). [PDF]

J Clin Oncol
Hernáiz Driever P, Kordes UR, Brecht IB, Saletti V, Fisher MJ, Doughton G, Arefayene M, Rigazio A, Lluch N, Llorente N, Diede SJ, Salvador H.   +11 more
europepmc   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

ZIP-ZnT1 complexes mediate a local Zn²⁺-cycle regulating neuronal Zn²⁺ transport. [PDF]

Cell Mol Life Sci
Nordio S, Asraf H, Bogdanovic M, Sekler I, Tzounopoulos T, Aizenman E, Hershfinkel M.   +6 more
europepmc   +1 more source

Simultaneous Enhancement of Mechanical and Dielectric Performance of Polypropylene Composites by Introducing an External Elastic Crystal

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A hierarchical crystalline structure for recyclable polypropylene insulation in high‐voltage cables is presented. This architecture integrates rigid isotactic polypropylene spherulites with an elastic crystalline network to balance load‐bearing capacity and ductility.
Guangwei Zhang, Zepeng Lv, Zhengbing Tian, Juntao Zhao, Dan Cao, Kai Wu, Thomas Andritsch   +6 more
wiley   +1 more source

Harnessing Ribonucleoprotein Granule Biology for Cancer Therapy: The Central Role of Protein Modifications. [PDF]

Research (Wash D C)
Li D, Yu Q, Wu R, Yoo KH, Wusiman D, Wang J, Zhang Q, Feng D.   +7 more
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Efficacy and safety of manufactured Chinese herbal formula for cervical radiculopathy: a systematic review with meta-analysis and trial sequential analysis. [PDF]

Front Neurosci
Tang B, Bao X, Li C, Gan W, Xu W, Zhang Y, Wu Z, Li Z, Huang B.   +8 more
europepmc   +1 more source

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

ELECTROPHORESIS, EarlyView.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam   +3 more
wiley   +1 more source