Partial Multi-Label Feature Selection via Entropy-Weighted Multi-Scale Neighborhood Granular Label Distribution Learning. [PDF]
Entropy (Basel)Cao Y +5 more
europepmc +1 more source
Relationship between hTERT levels and oxidative stress in epilepsy patients
Epilepsia Open, EarlyView.Abstract Objective Human telomerase reverse transcriptase (hTERT) is a key determinant of telomere maintenance and cellular aging. Oxidative stress plays a role in neurodegenerative processes by causing cellular damage through increased reactive oxygen species.
Muhammed Mehdi Üremiş +3 more
wiley +1 more source
Effects of Short-Term Synaptic Plasticity in Feedforward Inhibitory Circuits on Cerebellar Responses to Repetitive Sensory Input. [PDF]
J NeurosciHolla MR, Brown ST, Raman IM.
europepmc +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Epilepsia Open, EarlyView.Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source
When it's not Glanzmann thrombasthenia or Bernard-Soulier syndrome: diagnosing other qualitative platelet disorders. [PDF]
Hematology Am Soc Hematol Educ ProgramHayward CPM, Tasneem S.
europepmc +1 more source
Epilepsia Open, EarlyView.Abstract Objective The pathogenesis of epilepsy is closely associated with neuronal synaptic plasticity. MicroRNAs (miRNAs) can regulate various biological processes by binding to specific sequences on target genes. This study employs bioinformatics, molecular dynamics, and experimental approaches to investigate the mechanism by which MiR‐30a‐5p treats
Zhenlin Yang +4 more
wiley +1 more source
Insights into the potential mechanism of Beiqishen Jiangtang Granule in the treatment of type 2 diabetes nephropathy: A study based on network pharmacology, molecular docking, and biological validation. [PDF]
Medicine (Baltimore)Pan M +8 more
europepmc +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
Starch synthesis in Brachypodium distachyon endosperm occurs in dynamic, connected amyloplast compartments. [PDF]
New PhytolEsch L +6 more
europepmc +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska +6 more
wiley +1 more source