Results 161 to 170 of about 45,109,686 (250)

Stable organic radical qubits and their applications in quantum information science. [PDF]

Innovation (Camb)
Zhou A, Sun Z, Sun L.
europepmc   +1 more source

Applying interpretive phenomenological analysis to library and information science research on blended librarianship: A case study. [PDF]

Libr Inf Sci Res, 2020
Dabengwa IM, Raju J, Matingwina T.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Talent management of library and information science professionals: A review of research and future directions. [PDF]

F1000Res
Rautaray B, Swain DK, Swain C.
europepmc   +1 more source

Measuring researchers' potential scholarly impact with structural variations: Four types of researchers in information science (1979-2018). [PDF]

PLoS One, 2020
Hou J, Hou J, Yang X, Chen C.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science (1966)

, 1966
TENTH ANNUAL MEETING / April 2, 1966 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Arizona State University / Tempe, ArizonaThis volume is part of the Arizona-Nevada Academy of Science collections.
Arizona-Nevada Academy of Science
core  

Princípios científicos que direcionam a ciência e a tecnologia da informação digital

Transinformação
No quadro de um projeto epistemológico, apresenta-se um breve estudo crítico de cinco princípios científicos que direcionam e caracterizam, atualmente, os novos paradigmas informacionais presentes na Ciência e na Tecnologia da Informação Digital.
Yves-François Le Coadic
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Symposium of the Arizona-Nevada Academy of Science (1973)

, 1973
SEVENTEENTH ANNUAL MEETING / May 5, 1973 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona-Nevada Academy of Science ...
Arizona-Nevada Academy of Science
core