Results 161 to 170 of about 11,937,357 (296)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Das liest die LIBREAS, Nummer #1 (Sommer / Herbst 2017)

Library Ideas, 2017
Redaktion LIBREAS
doaj   +1 more source

Quantum Models of Consciousness from a Quantum Information Science Perspective. [PDF]

Entropy (Basel)
Gassab L, Pusuluk O, Cattaneo M, Müstecaplıoğlu ÖE.   +3 more
europepmc   +1 more source

Reimagining information science and technology beyond traditional boundaries in the global coronavirus pandemic situation. [PDF]

Proc Assoc Inf Sci Technol, 2020
Rorissa A, Li M, Young M, Turetsky D, Yuan XJ.   +4 more
europepmc   +1 more source

Computer Science vs Information Technology [PDF]

, 2014
Khar, A.T., Shulgin, Nikita, Zuyenok, I.I.   +2 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The role of information science within the clinical translational science ecosystem. [PDF]

J Clin Transl Sci
Ragon B, Seymour A, Whipple EC, Surkis A, Haberstroh A, Muilenburg J, Rethlefsen ML, Aspinall EE, Deaver J, Dexter N, Barger R, Contaxis N, Glenn EJ, Hinton E, Kern B, Little M, Pickett K, Sevetson E, Tao D, von Isenburg M, Werner DA, Wheeler TR, Holmes K.   +22 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Was ist Informationswissenschaft und wenn ja, wie viele? Ein Veranstaltungsbericht

Library Ideas, 2019
Carmen Krause
doaj   +1 more source

Stable organic radical qubits and their applications in quantum information science. [PDF]

Innovation (Camb)
Zhou A, Sun Z, Sun L.
europepmc   +1 more source