Results 161 to 170 of about 4,571,992 (304)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The Quantum Information Science Challenge for Chemistry. [PDF]

J Phys Chem Lett
Scholes GD, Olaya-Castro A, Mukamel S, Kirrander A, Ni KK, Hedley GJ, Frank NL.   +6 more
europepmc   +1 more source

Incorporating Geographic Information Science and Technology in Response to the COVID-19 Pandemic. [PDF]

Prev Chronic Dis, 2020
Smith CD, Mennis J.
europepmc   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 21 (1986)

, 1986
THIRTIENTH ANNUAL MEETING / April 19, 1986 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association / Glendale ...
Arizona-Nevada Academy of Science
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Novel extensions of k-harmonically convex functions and their applications in information science. [PDF]

PLoS One
Fahad A, Furuichi S, Ali Z, Wang Y.
europepmc   +1 more source

Journal of Information Science Theory and Practice [PDF]

, 2019
Korea Institute of Science and Technology Information
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Quantum Models of Consciousness from a Quantum Information Science Perspective. [PDF]

Entropy (Basel)
Gassab L, Pusuluk O, Cattaneo M, Müstecaplıoğlu ÖE.   +3 more
europepmc   +1 more source

Reimagining information science and technology beyond traditional boundaries in the global coronavirus pandemic situation. [PDF]

Proc Assoc Inf Sci Technol, 2020
Rorissa A, Li M, Young M, Turetsky D, Yuan XJ.   +4 more
europepmc   +1 more source