Results 231 to 240 of about 24,677,977 (386)

Assessment of the use of Open Educational Resources at five European Library and Information Science higher education institutions during and post-COVID-19 pandemic. [PDF]

Open Res Eur
Santos-Hermosa G, Urbano C, Argudo S, Boté-Vericad JJ, Đurđevic A, Micunovic M, Wöbbekind L, Todorova T.   +7 more
europepmc   +1 more source

A pesquisa discente nos cursos de graduação em biblioteconomia e ciência da informação

Transinformação
Discute-se a importância da pesquisa discente nos cursos de graduação em Biblioteconomia e Ciência da Informação. Enfocam-se os diferentes tipos e os níveis de participação dos alunos em projetos de pesquisa.
César Augusto Castro
doaj  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Educational strategies related to information science and technology for medical students: General medicine physicians' perspective. [PDF]

J Gen Fam Med
Shikino K, Tago M, Watari T, Sasaki Y, Takahashi H, Shimizu T.   +5 more
europepmc   +1 more source

Semantic Relativism and Information Science: An Exploration of District of Columbia v. Heller (2008)

, 2021
Elizabeth Zak
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Repositioning the Chemical Information Science Gateway. [PDF]

F1000Res, 2019
Bajorath J.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

An ethics and security course for students in computer science and information technology [PDF]

, 2006
Richard G. Epstein
openalex   +1 more source

Notas sobre o papel da pesquisa em cursos de graduação em ciência da informação

Transinformação
A pesquisa é atividade fundamental na formação de profissionais da informação. O termo pesquisa é associado aos conceitos de ciência e de complexidade, aspecto característico da ciência pós-moderna.
Nair Yumiko Kobashi
doaj