Results 61 to 70 of about 11,365,722 (324)

Macaw: An Extensible Conversational Information Seeking Platform [PDF]

open access: yesAnnual International ACM SIGIR Conference on Research and Development in Information Retrieval, 2019
Conversational information seeking (CIS) has been recognized as a major emerging research area in information retrieval. Such research will require data and tools, to allow the implementation and study of conversational systems.
Hamed Zamani, Nick Craswell
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Web information seeking by pages. World Wide Web, Information seeking, Personal development, Navigation

open access: yesInformation Research: An International Electronic Journal, 2004
The intention of this paper is to look at how the World Wide Web is used in looking for information in the domain of personal development. The theoretical aim of the paper is to elaborate conceptual tools for understanding better the content of Web pages,
Jarkko Kari
doaj  

A Meta-analysis of the factors affecting information seeking behavior in Iran and the world [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2020
Purpose: The aim of this study is to identify the components affecting information seeking behavior and to measure their impact from Persian and English articles in this field.
Elham Mirzaei   +2 more
doaj  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A process Approach to Information Services: Information Search Process (ISP) Model

open access: yesIranian Journal of Information Processing & Management, 2010
Information seeking is a behavior emerging out of the interaction between information seeker and information system and should be regarded as an episodic process so as to meet information needs of users and to take different roles in different stages of ...
Hamid Keshavarz, Abaas Eslami
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Internet Health Information Seeking and the Patient-Physician Relationship: A Systematic Review

open access: yesJournal of Medical Internet Research, 2017
Background With online health information becoming increasingly popular among patients, concerns have been raised about the impact of patients’ Internet health information-seeking behavior on their relationship with physicians. Therefore, it is pertinent

semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Information Seeking Behaviours of Historians

open access: yesTürk Kütüphaneciliği, 2013
Among user studies, which date to the 1940s, historians have become subject of various research since the 1970s. In this paper, historians’ information seeking behaviour is analyzed in terms of information sources, information channels, information ...
Hatice Gülşen Birinci
doaj  

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