Results 101 to 110 of about 11,522 (222)

Comparative Analysis of Two Elastic Types of Surface‐Crosslinked Gelatin Nanoparticles as Suitable Systems for Macromolecular Drug Delivery

Macromolecular Chemistry and Physics, EarlyView.
This study provides a development of surface‐crosslinked gelatin nanoparticles and explores their potential for the delivery of macromolecular drugs. The two nanoparticulate systems, consisting of either gelatin type A or B, display significantly different physicochemical and mechanical properties, with the latter evaluated by atomic force microscopy ...
Armin W. Novak, Stefan V. Pochmann, Alexander Horn, Agnes‐Valencia Weiss, Marc Schneider   +4 more
wiley   +1 more source

Effects of Skim Milk Whey‐Derived Proteins on Plasma, Urine, and Gut Metabolites in Preterm Piglets as a Model for Infants

Molecular Nutrition &Food Research, EarlyView.
The study aimed to evaluate how skim milk derived whey protein concentrate (SPC) in infant formula affects the gut, urine, and plasma metabolites of newborn piglets, in comparison to conventional whey protein concentrate (WPC). Preterm piglets were fed formula containing WPC, SPC, heat‐treated SPC (HT‐SPC), or stored HT‐SPC (HTSSPC) for five days ...
Yongxin Ye, Pingping Jiang, Karoline Aasmul‐Olsen, Halise Gül Akıllıoğlu, Ann Bjørnshave, Mie Rostved Bechshøft, Marianne Nissen Lund, Per Torp Sangild, Stine Brandt Bering, Bekzod Khakimov   +9 more
wiley   +1 more source

Nutraceuticals and COVID‐19: A mechanistic approach toward attenuating the disease complications

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
Abstract Nutraceuticals have emerged as potential compounds to attenuate the COVID‐19 complications. Precisely, these food additives strengthen the overall COVID treatment and enhance the immunity of a person. Such compounds have been used at a large scale, in almost every household due to their better affordability and easy access.
Keshav Raj Paudel, Vyoma Patel, Sukriti Vishwas, Saurabh Gupta, Sumit Sharma, Yinghan Chan, Niraj Kumar Jha, Jesus Shrestha, Mohammad Imran, Nisha Panth, Shakti Dhar Shukla, Saurav Kumar Jha, Hari Prasad Devkota, Majid Ebrahimi Warkiani, Sachin Kumar Singh, Md Khadem Ali, Gaurav Gupta, Dinesh Kumar Chellappan, Philip M. Hansbro, Kamal Dua   +19 more
wiley   +1 more source

Quality improvement for parenteral nutrition in hospital: Applying a gap analysis to an electronic health record to review parenteral nutrition processing

Nutrition in Clinical Practice, EarlyView.
Abstract Background In light of the complex and high‐risk nature of parenteral nutrition (PN), reviewing PN processing steps is essential to minimize patient harm. The main steps include ordering, verification, compounding, and administration. Electronic health records (EHRs) have become increasingly utilized and can play a critical role in enhancing ...
Andrea Kulyk, Jolayne Dahmer, Leah Gramlich   +2 more
wiley   +1 more source

Understanding how foods and enteral feedings influence the gut microbiome

Nutrition in Clinical Practice, EarlyView.
Abstract The gut microbiome supports both gut and overall health. Diet is known to be one of the driving factors that influences the gut microbiome. The foods we eat, the dietary and nondietary components they contain, various food consumption patterns, and the ratio of nutrients consumed have been shown to impact gut microbiome composition and ...
Gail A. M. Cresci
wiley   +1 more source

Liver‐directed drugs for transthyretin‐mediated amyloidosis

Journal of the Peripheral Nervous System, Volume 27, Issue 4, Page 228-237, December 2022., 2022
Abstract Transthyretin‐mediated amyloidosis (ATTR) is a rare, under‐recognized, progressively debilitating, fatal disease caused by the aggregation and extracellular deposition of amyloid transthyretin (TTR) fibrils in multiple organs and tissues throughout the body.
Thomas H. Brannagan 3rd, John L. Berk, Julian D. Gillmore, Mathew S. Maurer, Márcia Waddington‐Cruz, Marianna Fontana, Ahmad Masri, Laura Obici, Michela Brambatti, Brenda F. Baker, Lisa A. Hannan, Gustavo Buchele, Nick J. Viney, Teresa Coelho, Jose Nativi‐Nicolau   +14 more
wiley   +1 more source

A Facile Synthesis of 3‐Substituted Coumarins and Investigation of Their 3CLpro Inhibition Activity Against SARS‐CoV‐2

ChemistryOpen, EarlyView.
A user‐friendly protocol for the synthesis 3‐substituted coumarin derivatives was developed using Friedel‐Crafts alkylation and ozonolysis as key steps. Deactivation of 3‐chymotrypsin like protease (3CLpro) enzyme using these coumarin derivatives were investigated to explored their potential as 3CLpro inhibitors for Covid‐19 Therapeutics.
Manoj K. Choudhary, Khalid Ansari, Vivek Junghare, Sandip K. Nayak, Saugata Hazra, Soumyaditya Mula   +5 more
wiley   +1 more source

Factors that impact on the quality of life of intestinal failure patients treated with home parenteral nutrition: protocol for a multicentre, longitudinal observational study

BMJ Open
Background Home parenteral nutrition (HPN) refers to the intravenous administration of macronutrients, micronutrients and fluid. The aims of treatment are to increase survival and improve quality of life (QoL).
Mark Pearce, Nicholas P Thompson, David Jones, Colette Kirk, John Mathers   +4 more
doaj   +1 more source

Influencia de la formulación de la glutamina en sus efectos sobre los sistemas antioxidantes y de destoxificación hepática en la rata Effects of glutamine on antioxidants systems and hepatic detoxification in rats: influence of formulation

Nutrición Hospitalaria, 2004
Objetivos: El objeto de este estudio es valorar el efecto que la suplementación de dietas parenterales con L-glutamina o con L-alanil-L-glutamina ejerce sobre el equilibrio oxidante/antioxidante hepático y sobre los sistemas de destoxificación mediados ...
J. J. Ortiz de Urbina, F. Jorquera, J. Culebras, C. Villares, J. González-Gallego, M. J. Tuñón   +5 more
doaj  

Pharmacokinetics of continuous infusion ceftolozane/tazobactam in two patients with extensive total body surface area burns

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Introduction Treatment of infections in patients with burn injuries is challenging due to altered antimicrobial pharmacokinetics. Continuous infusion β‐lactam therapy may be a useful antimicrobial stewardship strategy to improve pharmacodynamic target attainment in this population.
Jay D. Olivet, Megan Amerson‐Brown, Juan J. Calix, Emma Graffice, Tyson Kilpatrick, Hanna F. Roenfanz, David P. Nicolau, Joseph L. Kuti, Matthew L. Brown   +8 more
wiley   +1 more source