Results 121 to 130 of about 11,255 (224)

Risk of Treatment Failure in Outpatient Parenteral Antimicrobial Therapy From an Academic Medical Center in Kentucky. [PDF]

open access: yesOpen Forum Infect Dis
Worsham Behal K   +5 more
europepmc   +1 more source

Digenic Functional B12 and Folate Defect Mimicking Myelodysplasia

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
Proposed mechanistic model of mutation‐related outcomes. ABSTRACT A digenic defect involving CUBN and MTHFR produced functional B12/folate deficiency in a patient with pancytopenia and neurological signs, mimicking myelodysplasia. Genetic and metabolic screening revealed elevated methylmalonic acid/homocysteine, with rapid remission post‐parenteral B12.
Thomas Cluzeau   +3 more
wiley   +1 more source

Fat overload syndrome in pediatric patients: One case and ten at risk. [PDF]

open access: yesAsia Pac J Clin Nutr
Saengpanit P   +3 more
europepmc   +1 more source

A causal inference framework to compare the effectiveness of life‐sustaining ICU therapies—using the example of cancer patients with sepsis

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 707-715, 1 February 2026.
What's new? Rising cancer incidence in the United States is associated with an increased demand on intensive care units (ICUs). Critically ill cancer patients, however, often rely on life‐sustaining therapies, which are linked to greater ICU mortality.
João Matos   +6 more
wiley   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

open access: yesJournal of Applied Toxicology, Volume 46, Issue 2, Page 682-696, February 2026.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros   +16 more
wiley   +1 more source

Association Between Abnormal DNA Methylation and Altered Transcriptome in Muscle Five Years After Critical Illness

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Critically ill patients requiring intensive care unit (ICU) admission suffer from muscle weakness that persists for years. Recently, altered RNA expression was documented in muscle of former ICU patients 5 years after critical illness that suggested disrupted mitochondrial function, disturbed lipid metabolism and fibrosis, of which ...
Ceren Uzun Ayar   +4 more
wiley   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon   +9 more
wiley   +1 more source

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