Results 131 to 140 of about 543,288 (335)

Challenges and opportunities in mitigating sarcoptic mange in wild South American camelids

open access: yesThe Journal of Wildlife Management, EarlyView.
Wild South American camelids—vicuña and guanaco—face threats from sarcoptic mange, a contagious skin disease linked to severe population declines. Despite its impact, major gaps remain in understanding disease dynamics. This review summarizes current knowledge, identifies key data and management gaps, and outlines urgent actions for effective ...
Alynn M. Martin   +13 more
wiley   +1 more source

GATA1 Transcriptionally Upregulates LMCD1, Promoting Ferroptosis in Sepsis‐Associated Acute Kidney Injury Through the Hippo/YAP Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) is associated with morbidity and mortality. Ferroptosis is associated with the pathophysiology of SA‐AKI. Here, we investigated the role of LIM and cysteine‐rich domain 1 (LMCD1) in the regulation of ferroptosis during SA‐AKI progression.
You‐Qi Zhang   +5 more
wiley   +1 more source

Small bowel and liver/small bowel transplantation in children. [PDF]

open access: yes, 1993
A clinical trial of intestinal transplantation was initiated at the University of Pittsburgh in May 1990. Eleven children received either a combined liver/small bowel graft (n = 8) or an isolated small bowel graft (n = 3).
Nour, B   +4 more
core  

Recognizing the Health Benefits of Plant‐Sourced Omega‐3 Stearidonic Acid: Exploring Its Complementary Role to Preformed EPA/DHA

open access: yesLipids, EarlyView.
ABSTRACT Long‐chain (LC) omega‐3 polyunsaturated fatty acids (PUFAs) like eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are crucial for optimal development, healthy aging, and disease management. Traditionally sourced from fatty fish, these omega‐3 PUFAs face sustainability challenges, prompting increased exploration of plant‐based ...
Ella J. Baker   +2 more
wiley   +1 more source

Age‐Dependent Finite Element Analysis of Microneedle Penetration into Human Skin: Influence of Insertion Velocity, and Microneedle's Geometry and Material

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study evaluates the combined effects of microneedle material, geometry, and insertion velocity on insertion force, considering the critical impact of age‐related variations in human skin. The results show that insertion force increases with age due to higher skin stiffness.
Pouria Azarikhah   +2 more
wiley   +1 more source

Bioavailability of Magnesium and Potassium Salts Used as Potential Substitutes for Sodium Chloride in Human Nutrition — A Review

open access: yesMolecular Nutrition &Food Research, EarlyView.
A high intake of sodium chloride contributes to hypertension. This review evaluates the bioavailability of potassium and magnesium salts as sodium chloride alternatives. Potassium chloride and citrate, as well as magnesium citrate and chloride, show good absorption.
Ronja Merschmann   +3 more
wiley   +1 more source

Influencia de la formulación de la glutamina en sus efectos sobre los sistemas antioxidantes y de destoxificación hepática en la rata Effects of glutamine on antioxidants systems and hepatic detoxification in rats: influence of formulation

open access: yesNutrición Hospitalaria, 2004
Objetivos: El objeto de este estudio es valorar el efecto que la suplementación de dietas parenterales con L-glutamina o con L-alanil-L-glutamina ejerce sobre el equilibrio oxidante/antioxidante hepático y sobre los sistemas de destoxificación mediados ...
J. J. Ortiz de Urbina   +5 more
doaj  

Factors that impact on the quality of life of intestinal failure patients treated with home parenteral nutrition: protocol for a multicentre, longitudinal observational study

open access: yesBMJ Open
Background Home parenteral nutrition (HPN) refers to the intravenous administration of macronutrients, micronutrients and fluid. The aims of treatment are to increase survival and improve quality of life (QoL).
Mark Pearce   +4 more
doaj   +1 more source

Stealth Drug Delivery of Mouse Serum Albumin‐Coated Paclitaxel‐Loaded Gelatin Nanoparticles for Targeted Cancer Therapy in Mice

open access: yesNano Select, EarlyView.
Our study presents a novel approach to localized cancer therapy by developing mouse serum albumin (MSA)‐coated paclitaxel (PTX)‐loaded gelatin nanoparticles (MSA@PTX‐loaded GNPs) as a stealth drug delivery system. Given the challenges of nanoparticle‐based chemotherapy, including rapid opsonization and limited drug accumulation at tumor sites, our work
Md. Annur Sadman   +10 more
wiley   +1 more source

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