Results 181 to 190 of about 636,834 (344)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Safety analysis of self-administered enzyme replacement therapy using data from the Fabry Outcome and Gaucher Outcome Surveys. [PDF]

Orphanet J Rare Dis
Revel-Vilk S, Ramaswami U, Pintos-Morell G, Hughes D, Nicholls K, Reisin R, Giugliani R, Goker-Alpan O, Istaiti M, Gill A, Scarpa M, Botha J.   +11 more
europepmc   +1 more source

RAPID COLD PLASMA INFUSION TREATMENT FOR SEVERE SHOCK (PERIPHERAL FAILURE) FOLLOWING CORONARY OCCLUSION† [PDF]

, 1958
Arthur Vogelsang
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

The clinical characteristics of patients with congenital nephrotic syndrome secondary to NPHS1 mutation: Is nephrectomy still a therapeutic option for selected cases? [PDF]

Pediatr Nephrol
Uğurlu Y, Gülhan B, Dursun İ, Nalçacıoğlu H, Kaya Aksoy G, Canpolat N, Bayazıt A, Özçakar ZB, Yüksel S, Parmaksız G, Özdemir G, Kurt-Şükür ED, Düzova A, Hayran M, Ozaltin F.   +14 more
europepmc   +1 more source

The formation of liver glycogen in the cat, under various conditions, following infusion of ammonium lactate

, 1933
R. T. Grant
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Effect of extended intravenous diclofenac infusions on brain tissue oxygenation in patients with acute brain injury. [PDF]

Intensive Care Med Exp
Klug J, Cortier D, Wolf S, Carrera E, Cerf C, Pietsch U.   +5 more
europepmc   +1 more source

THE USE OF CULTURE MEDIA MADE FROM COMMERCIAL DRIED YEAST AS A ROUTINE SUBSTITUTE FOR MEAT INFUSION PEPTONE MEDIA [PDF]

, 1929
James M. Neill, John Y. Sugg, Lurline V. Richardson, William L. Fleming   +3 more
openalex   +1 more source

Thiopentone infusions [PDF]

Anaesthesia, 1980
M, Helliwell, R J, Flanagan
openaire   +2 more sources