Results 101 to 110 of about 27,747 (308)

Analysis of Human Motion Data for Vehicle Ingress Discomfort Evaluation [PDF]

open access: yes, 2015
The ease of entering a vehicle, known as ingress, is one of the important ergonomic factors that car manufacturers consider during the process of vehicle design.
Masoud, Hadi Ibrahim
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Phenomenology of Graphite Burning in Air Ingress Accidents of HTRs

open access: yesScience and Technology of Nuclear Installations, 2011
Air ingress with graphite burning belongs to the accident scenarios in HTRs with potentially severe consequences. This paper gives an overview of basic phenomena of graphite burning like ignition conditions and moving reaction fronts.
Rainer Moormann
doaj   +1 more source

Patterns of Larval Atlantic Croaker Ingress into Chesapeake Bay, USA

open access: yes, 2009
We compared ingress patterns of Atlantic croaker Micropogonias undulatus larvae into Chesapeake Bay, USA, with published ingress patterns through barrier island inlets, the accepted model for larval fish ingress. This model asserts that larvae ingress on
Jones, Cynthia M.   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Perpendicular-to-crack chloride ingress in cracked and autonomously healed concrete

open access: yesMATEC Web of Conferences, 2018
Cracks in reinforced concrete structures exposed to a marine environment or de-icing salts can cause major durability issues due do accelerated ingress of chloride ions.
Van Belleghem Bjorn   +3 more
doaj   +1 more source

HTTPProxy Inclusion for Contour Ingress Controller Microservice

open access: yes
Cloud-native applications require efficient HTTP routing for scalable, resilient, and secure service management, especially within Kubernetes environments.
Hmida, Salim
core  

Analysis on the Density Driven Air-Ingress Accident in VHTRs [PDF]

open access: yes, 2008
Air-ingress following the pipe rupture is considered to be the most serious accident in the VHTRs due to its potential problems such as core heat-up, structural integrity and toxic gas release.
Petti, David   +3 more
core  

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