Results 81 to 90 of about 98,970 (350)

Theoretical modelling of hot gas ingestion through turbine rim seals

Propulsion and Power Research, 2012
The rim seals of gas turbines are used to prevent or reduce the ingestion of hot mainstream gas into the wheel-space between the turbine rotor and its adjacent stationary casing.
J. Michael Owen
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A SDN-Based Vehicular Mobility Management for a Shared-Prefix Model Over IEEE WAVE IPv6 Networks

IEEE Access
IETF IP WAVE Working Group proposes a vehicular mobility management scheme with a shared-prefix model that multiple RSUs share a common prefix. When using a shared-prefix model, a WAVE wireless interface on a vehicle does not need to reconfigure its IPv6
Myeongji Ko, Hyeonhui Jeon, Hyogon Kim, Sung-Gi Min   +3 more
doaj   +1 more source

Estimating Corrosion Initiation Period Due to Chloride Ingress into Reinforced Self-Compacting Concrete Incorporating High Volume Fly Ash

MATEC Web of Conferences, 2017
One of the main sources of reinforcement corrosion is the ingress of chloride ion into a concrete structure. The rate of chloride ingress and its consequence to initiate corrosion could determine the service life of the structure.
Kristiawan Stefanus, Wibowo, Sunarmasto, Gan Buntara S, Nurrohmah Septina   +4 more
doaj   +1 more source

Long-term, multiwavelength light curves of ultra-cool dwarfs: II. The evolving light curves of the T2. 5 SIMP 0136 & the uncorrelated light curves of the M9 TVLM 513 [PDF]

, 2016
We present multiwavelength, multi-telescope, ground-based follow-up photometry of the white dwarf WD 1145+017, that has recently been suggested to be orbited by up to six or more, short-period, low- mass, disintegrating planetesimals.
Croll, B., Dalba, P. A., Han, E., Lichtman, J., Muirhead, P. S., Radigan, J.   +5 more
core   +1 more source

Distributed Optimization of Multi-Cell Uplink Co-operation with Backhaul Constraints

, 2015
We address the problem of uplink co-operative reception with constraints on both backhaul bandwidth and the receiver aperture, or number of antenna signals that can be processed.
Honig, Michael L., Nagaraj, Shirish, Zeineddine, Khalid   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Towards consistent mapping of distant worlds: secondary-eclipse scanning of the exoplanet HD189733b

, 2012
Mapping distant worlds is the next frontier for exoplanet infrared photometry studies. Ultimately, constraining spatial and temporal properties of an exoplanet atmosphere will provide further insight into its physics. For tidally-locked hot Jupiters that
de Wit, Julien, Demory, Brice-Olivier, Gillon, Michaël, Seager, Sara   +3 more
core   +1 more source