Results 81 to 90 of about 27,747 (308)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

GPR Raw-Data Order Statistic Filtering and Split-Spectrum Processing to Detect Moisture

open access: yesRemote Sensing, 2014
Considerable research into the area of bridge health monitoring has been undertaken; however, information is still lacking on the effects of certain defects, such as moisture ingress, on the results of ground penetrating radar (GPR) surveying.
Gokhan Kilic
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Chloride ingress testing of concrete

open access: yes, 2015
Concrete is recognised as a durable material that can provide long-term protection to embedded carbon steel reinforcement. However, effective protection can only be achieved if the mechanisms of deterioration and the durability properties of the ...
Christian Christodoulou (7175462)   +4 more
core   +2 more sources

Mechanical Performance and Chloride Diffusivity of Cracked RC Specimens Exposed to Freeze-Thaw Cycles and Intermittent Immersion in Seawater

open access: yesAdvances in Materials Science and Engineering, 2016
The effects of crack width on chloride ingress and mechanical behavior of reinforced concrete (RC) specimens were experimentally studied after exposure to 300 cycles of freeze-thaw and seawater immersion (75 times).
Bei Shen   +3 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

The effect of hydrophobic (silane) treatment on concrete durability characteristics

open access: yesMATEC Web of Conferences, 2018
Hydrophobic (silane) impregnation represents a cost-effective way to increase the durability of concrete structures in cases where insufficient design cover quality and depth have been achieved.
Sohawon Haris, Beushausen Hans
doaj   +1 more source

Chloride Ingress in a Swedish Road Environment

open access: yes, 2002
Concrete blocks have been exposed up to five winters at a field station along the motorway Rv40 west of Borås, some 60 km from the Swedish west coast. The concrete mixes are made from a number of Nordic cements and other types of binders (fly ash, silica
Lindvall, Anders
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Epidemiology of Diagnosed Age-related Macular Degeneration in Germany: An Evaluation of the Prevalence Using AOK PLUS Claims Data

open access: yesOphthalmology and Therapy
Introduction Epidemiologic data on age-related macular degeneration (AMD) are mainly based on cohort studies, including both diagnosed and undiagnosed cases.
Alexander K. Schuster   +7 more
doaj   +1 more source

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