Results 111 to 120 of about 352,671 (284)
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia +29 more
wiley +1 more source
Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core +1 more source
Goal of the study: to assess the feasibility of using inhalation anesthetics of desflurane and sevoflurane during cardiopulmonary bypass to reduce the chances of post-perfusion cardiac dysfunction during myocardial revasculization surgeries.
N. S. Molchan +4 more
doaj +1 more source
Role of SLC16A10 in Psoriasis Through the Regulation of Arachidonic Acid Metabolism in Keratinocytes
This study demonstrates that SLC16A10 plays a crucial role in psoriasis pathogenesis through arachidonic acid metabolism regulation in keratinocytes. Using multi‐omics analysis and experimental validation, researchers identify SLC16A10 as both a diagnostic biomarker and therapeutic target.
Jingyuan Yang +17 more
wiley +1 more source
A NEW METHOD OF DEPICTING RESISTANCE OF INHALATION ANESTHETIC EQUIPMENT [PDF]
William K. Hamilton, DOUGLAS W. EASTWOOD
openalex +1 more source
Compared to transplantation of neural stem cells (NSCs) alone, the combined treatment of NSCs with semaglutide more effectively improves motor dysfunction in Parkinson's disease (PD) mice. This synergistic effect may result from semaglutide's ability to suppress microglial activation, thereby preventing the transformation of resting astrocytes into ...
Dan Song +6 more
wiley +1 more source
The Effect of Inhalation Anesthetics on Repetitive Activity Generated at Motor Nerve Endings [PDF]
Alan Van Poznak
openalex +1 more source
Neuroprotective Properties of Xenon. [PDF]
Xenon is a rare noble gas that was introduced into clinical practice more than 70 years ago. Xenon's clinical properties are predicated by its ability to fit into preformed cavities of macromolecules thereby altering their biological functions.
Laitio, Timo, Maze, Mervyn
core
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser +11 more
wiley +1 more source
DETERMINATION OF THE PARTIAL PRESSURE OF HALOTHANE (OR ISOFLURANE) IN BLOOD [PDF]
A gas chromatographic method is described for the direct quantitative determination of the partial pressure of halothane {or isoflurane) in blood as well as the blood-gas partition coefficient.
FREI, F. J. +4 more
core

