Results 31 to 40 of about 10,464 (256)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

CLINICAL AND ECONOMIC EVALUATION OF INHALATION ANESTHETICS USE

open access: yesВестник анестезиологии и реаниматологии, 2018
Sevoflurane is one of the widely used inhalation anesthetics as well as desflurane, which started to be used in Russia in 2012. These drugs possess similar properties; however, desflurane provides faster restoration of cognitive functions and reduces the
R. R. Gubaydullin   +2 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Modern aspects in anesthesia of small laboratory animals

open access: yesЮжно-Российский онкологический журнал, 2022
Experiments with small laboratory animals are required for better understanding of a disease flow, for studying the mechanisms of it’s development and for the development of new therapeutic strategies.
S. V. Gurova   +2 more
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang   +10 more
wiley   +1 more source

Comparison of surgical field visibility during propofol or desflurane anesthesia for middle ear microsurgery

open access: yesBMC Anesthesiology, 2019
Background To compare surgical field visibility between patients given propofol/remifentanil (PR) or desflurane/remifentanil (DR) anesthesia. Methods A total of 80 adult patients undergoing middle ear microsurgery due to cholesteatoma otitis media with ...
Xia Yuan   +3 more
doaj   +1 more source

Isoflurane induces Art2‐Rsp5‐dependent endocytosis of Bap2 in yeast

open access: yesFEBS Open Bio, 2021
Although general anesthesia is indispensable during modern surgical procedures, the mechanism by which inhalation anesthetics act on the synaptic membrane at the molecular and cellular level is largely unknown.
Fumi Kozu   +5 more
doaj   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee   +4 more
wiley   +1 more source

Sedative Agents, Synthetic Torpor, and Long-Haul Space Travel—A Systematic Review

open access: yesLife
Background: With renewed interest in long-duration space missions, there is growing exploration into synthetic torpor as a countermeasure to mitigate physiological stressors.
Thomas Cahill   +5 more
doaj   +1 more source

Comparative Evaluation of Modern Inhalation Anesthetics in Carotid Endarterectomy

open access: yesОбщая реаниматология, 2019
The purpose of the study was to compare the possibility of rapid activation of elderly patients after carotid endarterectomy performed under sevoflurane- or desflurane-based anesthesia. Materials and methods.
V. A. Aliev   +4 more
doaj   +1 more source

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