Results 41 to 50 of about 20,702 (173)

Anesthesia and Oncology: Friend or Foe?

Frontiers in Oncology, 2022
Cancer is a leading cause of death, and surgery is an important treatment modality. Laboratory research and retrospective studies have raised the suspicion that the choice of anesthetics for cancer surgery might affect the course of cancerous disease ...
Bigna S. Buddeberg, Bigna S. Buddeberg, Manfred D. Seeberger   +2 more
doaj   +1 more source

A Retrospective Study on Time Impact of Major Trauma Patients Requiring Access to the Operating Room on the Anesthesia Department of a Pediatric Trauma Center

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Trauma is one of the leading causes of death in children. Trauma patients have been demonstrated to require significant resources, including operating room time. We aimed to describe the characteristics and patterns of access to surgery and outcomes of pediatric major trauma patients at The Hospital for Sick Children.
Ruth Bird, Martina Bordini, Suzanne Beno, Clyde T. Matava   +3 more
wiley   +1 more source

Outcomes of intravenous and inhalation anesthesia on patients undergoing esophageal cancer surgery: a retrospective observational study

BMC Anesthesiology, 2023
Background Different anesthetics may have opposite effects on the immune system, thus affecting the prognosis of tumor patients. Cell-mediated immunity forms the primary defense against the invasion of tumor cells, so manipulation of the immune system to
Yue Ma, Jie Ren, Zhuo Chen, Jingwen Chen, Ming Wei, Yu Wang, Hong Chen, Liping Wang   +7 more
doaj   +1 more source

Current Use, Monitoring and Reversal of Neuromuscular Block in Pediatric Anesthesia and Intensive Care: A Web‐Based Cross‐Sectional ESAIC Survey

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Neuromuscular blocking agents are recommended by the European Society of Anaesthesiology and Intensive Care (ESAIC) and European Society of Paediatric Anaesthesia (ESPA) for facilitating tracheal intubation in children. Despite these recommendations, real‐world data on how neuromuscular blocking agents are used, monitored, and ...
Giulia Bonatti, Mirjana Gander, Arash Afshari, Francis Veyckemans, Thomas Fuchs‐Buder, Thomas Riva, Markus Huber, Nicola Disma, Alexander Fuchs   +8 more
wiley   +1 more source

Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics

, 2003
Anesthetics exert multiple effects on the central nervous system through altering synaptic transmission, but the mechanisms for this process are poorly understood.
Tao, Yuan Xiang, Mao, Peizhong, Levine, Claire F., Chou, Chih Ling, Sadegh-Nasseri, Scheherazade, Zhang, Mingjie, Johns, Roger A., He, Fahu, Tao, Feng, Fang, Ming   +9 more
core   +1 more source

Comparison of Intravenous Vs. Inhalational Anesthetics in Pediatric Surgery: A Cross-Sectional Analysis [PDF]

Background: Anesthetic choice in pediatric surgery impacts patient outcomes, recovery times, and safety. This study compares the efficacy and safety of intravenous (IV) versus inhalational anesthetics in a pediatric surgical population.
Swetha P
core   +1 more source

Desflurane - Revisited

Journal of Anaesthesiology Clinical Pharmacology, 2012
The search for an ideal inhalational general anesthetic agent continues. Desflurane, which was recently introduced in the Indian market, possesses favorable pharmacokinetic and pharmacodynamic properties and is closer to the definition of an ideal agent.
Mukul Chandra Kapoor, Mahesh Vakamudi
doaj   +1 more source

A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly

Scientific Reports, 2021
Anesthetics are deemed necessary for all major surgical procedures. However, they have also been found to exert neurotoxic effects when tested on various experimental models, but the underlying mechanisms remain unknown.
Fahad Iqbal, Marcus Pehar, Andrew J. Thompson, Urva Azeem, Kiana Jahanbakhsh, Nerea Jimenez-Tellez, Rasha Sabouny, Shadab Batool, Atika Syeda, Jennifer Chow, Pranav Machiraju, Timothy Shutt, Kamran Yusuf, Jane Shearer, Tiffany Rice, Naweed I. Syed   +15 more
doaj   +1 more source

A Sedation Protocol for Endoscopic Baton‐Plate Adjustment in Neonates With Pierre Robin Sequence

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Robin sequence (RS) is characterized by upper airway obstruction leading to life‐threatening desaturations in neonates. Procedural sedation in this population presents unique challenges due to anatomical airway anomalies, young patient age, and associated comorbidities.
Nicolas Leister, Sarah Achterrath, Uwe Trieschmann, Teresa Kruse, Bert Braumann, Volker C. Schick   +5 more
wiley   +1 more source

Inhalational Anesthetics Do Not Deteriorate Amyloid-beta-Derived Pathophysiology in Alzheimer's Disease: Investigations on the Molecular, Neuronal, and Behavioral Level

, 2021
Background: Studies suggest that general anesthetics like isoflurane and sevoflurane may aggravate Alzheimer's disease (AD) neuropathogenesis, e.g., increased amyloid-beta (A beta) protein aggregation resulting in synaptotoxicity and cognitive ...
Hadian, K., Borgstedt, L., Ebert, T., Jungwirth, B., Rammes, G., Buerge, M., Kopp, C., Wotjak, C., Kreuzer, M., Hofmann, C., Sander, A., Schorpp, K., Ruitenberg, M., Wang, X., Parsons, C.   +14 more
core   +1 more source