Results 91 to 100 of about 424,292 (310)

Astrocytes-associated research in Parkinson’s disease: an explored trends analysis

Frontiers in Aging Neuroscience
BackgroundParkinson’s disease (PD) is characterized pathologically by the degeneration of dopaminergic neurons and the formation of Lewy bodies. Among the various cellular and molecular mechanisms of PD, astrocyte dysfunction is one of the causes of ...
Yan-Jun Chen, Yan-Jun Chen, Ming-Rong Xie, Sheng-Qiang Zhou, Fang Liu   +4 more
doaj   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Glutamate-associated research in Parkinson’s disease: a bibliometric analysis

Frontiers in Aging Neuroscience
BackgroundParkinson’s disease (PD) is a common neurodegenerative disease. As an important excitatory neurotransmitter, glutamate plays a key role in the nervous system.
Yan-Jun Chen, Yan-Jun Chen, Ming-Rong Xie, Sheng-Qiang Zhou, Fang Liu   +4 more
doaj   +1 more source

3D Printing Innovations in Polymeric Porous and Patterned Architecture

Advanced Functional Materials, EarlyView.
Polymeric foams occupy a unique structural space between dense solids and open networks, where engineered void fraction governs mechanical compliance, thermal resistance, and mass transport. Additive manufacturing now enables precise spatial control over cellular architecture, unlocking designer foam structures across applications spanning crash ...
Dhanush Patil, Sri Vaishnavi Thummalapalli, Clarissa Westover, Arunachalam Ramanathan, M. Taylor Sobzcak, Roumika Patil, Qixuan Xiang, Tiantian Li, Sui Yang, Timothy E. Long, Hongyue Sun, Xianqiao Wang, Yang Liu, Kenan Song   +13 more
wiley   +1 more source

Mapping the research of mitochondria and Parkinson’s disease: a bibliometric analysis

Frontiers in Neurology
BackgroundParkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder primarily affecting the elderly. Relevant studies suggest a significant connection between the mitochondria and PD.
Yan-Jun Chen, Yan-Jun Chen, Ming-Rong Xie, Sheng-Qiang Zhou, Fang Liu   +4 more
doaj   +1 more source

Spatially Decoupling Heating and Evaporation for Convection‐Enhanced 3D Solar Evaporation With Continuous Salt Harvesting

Advanced Functional Materials, EarlyView.
An architecture‐enabled bottom‐heated 3D solar convective evaporator spatially decouples photothermal heating from evaporation, triggering natural convection that intensifies sidewall vapour removal and heat transfer. The system achieves significantly enhanced evaporation rates over 2D and conventional 3D designs while confining salt precipitation to ...
Xiaolong Ma, Yan Zhao, Yan Yan, Muhammad Amjad, Guice Yao, Hui Gao, Shudan Wei, Dongsheng Wen   +7 more
wiley   +1 more source

Microglia-associated research in Parkinson’s disease: a bibliometric analysis

Frontiers in Aging Neuroscience
BackgroundParkinson’s disease (PD) is a neurodegenerative disorder that predominantly affects the elderly. Evidence indicates that microglia-mediated neuroinflammation is recognized as one of the key mechanisms in PD.
Yan-Jun Chen, Yan-Jun Chen, Ming-Rong Xie, Sheng-Qiang Zhou, Fang Liu   +4 more
doaj   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Hypoxia-Induced Adaptations of Embryonic Fibroblasts: Implications for Developmental Processes

Biology
Animal embryonic development occurs under hypoxia, which can promote various developmental processes. Embryonic fibroblasts, which can differentiate into bone and cartilage and secrete various members of the collagen protein family, play essential roles ...
Zeyu Li, Delong Han, Zhenchi Li, Lingjie Luo   +3 more
doaj   +1 more source