Results 111 to 120 of about 819,324 (310)

Selection theorem for systems with inheritance

, 2007
The problem of finite-dimensional asymptotics of infinite-dimensional dynamic systems is studied. A non-linear kinetic system with conservation of supports for distributions has generically finite-dimensional asymptotics.
Gorban, A. N.
core   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Metabolic Engineering of Terpenoid Biosynthesis in Medicinal Plants: From Genomic Insights to Biotechnological Applications

Current Issues in Molecular Biology
Terpenoids, which are essential pharmaceutical compounds, encounter significant production challenges due to their low yields in native plants and associated ecological concerns.
Changfeng Guo, Si Xu, Xiaoyun Guo
doaj   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Genotyping-by-sequencing of Illicium difengpi highlights its potential genetic diversity and conservation status

Scientific Reports
Illicium difengpi is a critically endangered plant endemic to the karst mountains of Guangxi, China. Because of its medicinal and ecological values, many efforts were made on assessing the medicinal usage, natural history, ex-situ conservation, and ...
Ben Qin, Ying Hu, Yanfen Huang, Ying Liang, Xiaoyun Guo, Baoyou Huang   +5 more
doaj   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Inherited Cardiomyopathies

New England Journal of Medicine, 2011
Schwartz, Robert S., Watkins, Hugh, Ashrafian, Houman, Redwood, Charles   +3 more
openaire   +3 more sources

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Identification of key modules and genes in response to high-temperature stress in Platostoma palustre based on WGCNA

BMC Plant Biology
Platostoma palustre (Blume) A. J. Paton is one of the important medicinal and edible plants in China, and it is widely cultivated in tropical and subtropical regions of southern China.
Xiufang Li, Fan Wei, Changqian Quan, Meihua Xu, Danfeng Tang   +4 more
doaj   +1 more source

Gifts and inheritances in Ireland. ESRI WP579, December 2017 [PDF]

, 2017
Information on the frequency, value and composition of household wealth transfers has been fairly limited in Ireland and this paper aims to fill this gap by drawing on the detailed data now available on the pattern of gifts and inheritances from the 2013
Lawless, Martina, Lynch, Donal
core