Results 191 to 200 of about 517,479 (253)

Patient‐reported outcomes and visual function after four refractive strategies in cataract surgery: A randomized controlled trial

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate patient‐reported outcome measures (PROMs) and visual function across four groups of public cataract patients: emmetropia, mini‐monovision, monovision with partial‐range of field (RoF) narrow intraocular lenses (IOLs) and patients implanted with partial‐RoF extended IOLs.
Anne Guldhammer Skov, Morten la Cour, Birgitte Moldow, Lars Holm, Therese Krarup   +4 more
wiley   +1 more source

Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration. [PDF]

Commun Biol
Fry LE, Major L, Salman A, McDermott LA, Yang J, King AJ, McClements ME, MacLaren RE.   +7 more
europepmc   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

Preservation of vision by transpalpebral electrical stimulation in mice with inherited retinal degeneration. [PDF]

Front Cell Dev Biol
Gunes K, Chang K, Lennikov A, Tai WL, Chen J, ElZaridi F, Cho KS, Utheim TP, Dong Feng C.   +8 more
europepmc   +1 more source

Clinical and Genetic Re-Evaluation of Inherited Retinal Degeneration Pedigrees following Initial Negative Findings on Panel-Based Next Generation Sequencing. [PDF]

Int J Mol Sci, 2022
Stephenson KAJ, Zhu J, Dockery A, Whelan L, Burke T, Turner J, O'Byrne JJ, Farrar GJ, Keegan DJ.   +8 more
europepmc   +1 more source

Radial outer retina reflectivity (RORR) sign in LAMP2‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the radial outer retina reflectivity (RORR) sign in patients carrying pathogenic variants in the X‐linked lysosome‐associated membrane protein‐2 (LAMP2) gene and to review the histologic characteristics of LAMP2 expression in the human retina.
Rachael C. Heath Jeffery, Bohdan Kousal, Ulrike Grünert, Christine A. Curcio, Svetlana Cherepanoff, Tina M. Lamey, Michel Michaelides, Chrysanthi Tsika, Isabelle Chow, Omar A. Mahroo, Seungmin Lee, Martin Meliska, Milos Kubanek, Jakub Sikora, Siying Lin, Raymond C. B. Wong, Petra Liskova, Fred K. Chen   +17 more
wiley   +1 more source

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

Relationship between genotype, phenotype, and refractive status in patients of inherited retinal degeneration. [PDF]

Eye (Lond)
Tsai WC, Liu YL, Tsai TH, Lai YJ, Yang CH, Yang CM, Ho TC, Lin CP, Hsieh YT, Yeh PT, Lin CW, Lai TT, Chen PL, Chen TC.   +13 more
europepmc   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor. [PDF]

Cell Death Dis
Yang M, Yao J, Jia L, Kocab AJ, Zacks DN.   +4 more
europepmc   +1 more source