Results 1 to 10 of about 6,364,217 (385)

Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation

BMC Chemistry, 2021
Background Presently available chemical based synthetic preservative have emerged with various side effects, so the aspiration of natural and side effect free novel preservative has been greatly increased.
Amit Lather, Sunil Sharma, Anurag Khatkar   +2 more
doaj   +1 more source

Antimicrobial Activity the Essential Oil from Croton pluriglandulosus Carn. Leaves against Microorganisms of Clinical Interest

Journal of Fungi, 2023
Multiresistant pathogens pose a serious threat to human health. The genus Candida is one class of human pathogenic yeasts responsible for infections affecting healthy and immunocompromised patients.
Rayara J. P. Carvalho, Pedro F. N. Souza, Ellen A. Malveira, Nilton A. S. Neto, Romério R. S. Silva, Gabriel L. C. Melo, Ayrles F. B. Silva, Leandro B. Lima, Cynthia C. de Albuquerque, Rafael W. Bastos, Gustavo H. Goldman, Cleverson D. T. de Freitas   +11 more
doaj   +1 more source

Links between Neuroanatomy and Neurophysiology with Turning Performance in People with Multiple Sclerosis

Sensors, 2023
Multiple sclerosis is accompanied by decreased mobility and various adaptations affecting neural structure and function. Therefore, the purpose of this project was to understand how motor cortex thickness and corticospinal excitation and inhibition ...
Clayton W. Swanson, Brett W. Fling
doaj   +1 more source

Cystatins from the Human Liver Fluke Opisthorchis viverrini: Molecular Characterization and Functional Analysis

Pathogens, 2023
A high incidence of cholangiocarcinoma (bile duct cancer) has been observed in Thailand. This usually rare cancer has been associated with infection with the human liver fluke, Opisthorchis viverrini.
Amornrat Geadkaew-Krenc, Rudi Grams, Sinee Siricoon, Nanthawat Kosa, Dawid Krenc, Wansika Phadungsil, Pongsakorn Martviset   +6 more
doaj   +1 more source

Naringin derivatives as glucosamine-6-phosphate synthase inhibitors based preservatives and their biological evaluation

Scientific Reports, 2020
Glucosamine-6-Phosphate synthase enzyme has been targeted for development of better and safe preservative due to its role in microbial cell wall synthesis.
Amit Lather, Sunil Sharma, Anurag Khatkar   +2 more
doaj   +1 more source

Probing the Influence of Novel Organometallic Copper(II) Complexes on Spinach PSII Photochemistry Using OJIP Fluorescence Transient Measurements

Biomolecules, 2023
Modern agricultural cultivation relies heavily on genetically modified plants that survive after exposure to herbicides that kill weeds. Despite this biotechnology, there is a growing need for new sustainable, environmentally friendly, and biodegradable ...
Sergei K. Zharmukhamedov, Mehriban S. Shabanova, Irada M. Huseynova, Mehmet Sayım Karacan, Nurcan Karacan, Hande Akar, Vladimir D. Kreslavski, Hesham F. Alharby, Barry D. Bruce, Suleyman I. Allakhverdiev   +9 more
doaj   +1 more source

Methylthiosulfonate-Based Cysteine Modifiers as Alternative Inhibitors of Mercurial-Sensitive Aquaporins

Cells, 2023
(1) Background: Several members of the ubiquitous aquaporin family, AQP, of water and neutral solute channels carry a cysteine residue in the selectivity filter region. Traditionally, toxic mercury-containing compounds are used to bind to the cysteine as
Katrin Jeuken, Emmi Jaeger, Emily Matthews, Eric Beitz   +3 more
doaj   +1 more source

Naringenin derivatives as glucosamine-6-phosphate synthase inhibitors: synthesis, antioxidants, antimicrobial, preservative efficacy, molecular docking and in silico ADMET analysis

BMC Chemistry, 2020
Background Preservatives have to be added in food, pharmaceuticals and cosmetics products to maintain their shelf life. However, the existing chemical based preservatives have been associated with severe side effects that compel the researchers to find ...
Amit Lather, Sunil Sharma, Anurag Khatkar   +2 more
doaj   +1 more source

Lead optimization for promising monoamine oxidase inhibitor from eugenol for the treatment of neurological disorder: synthesis and in silico based study

BMC Chemistry, 2019
Natural based inhibitors of monoamine oxidase are promising drug candidates for the treatment of several neurodegenerative and neuropsychological disorders including depression, anxiety, Parkinson’s disease and Alzheimer’s disease.
Priyanka Dhiman, Neelam Malik, Anurag Khatkar   +2 more
doaj   +1 more source

Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies

BMC Chemistry, 2020
Neurodegenerative disorders follow numerous pathological ways concerning overexpression of monoamine oxidase and formation of reactive oxygen species.
Priyanka Dhiman, Neelam Malik, Anurag Khatkar   +2 more
doaj   +1 more source