Results 1 to 10 of about 6,274,440 (386)

Aesculin based glucosamine-6-phosphate synthase inhibitors as novel preservatives for food and pharmaceutical products: in-silico studies, antioxidant, antimicrobial and preservative efficacy evaluation

BMC Chemistry, 2021
Background Presently available chemical based synthetic preservative have emerged with various side effects, so the aspiration of natural and side effect free novel preservative has been greatly increased.
Amit Lather, Sunil Sharma, Anurag Khatkar   +2 more
doaj   +1 more source

Long-Term Limitation Effects of Se(VI), Zn(II), and Ni(II) on Start-Up of the Anammox Process Using Gel Carrier

Frontiers in Bioengineering and Biotechnology, 2022
Anaerobic ammonia oxidation (anammox) bacteria are inhibited by heavy metals at high concentrations but require trace amounts of some heavy-metal elements for growth and activity maintenance.
Kazuichi Isaka, Daichi Sugawara, Hiroshi Yamazaki, Yuya Kimura, Toshifumi Osaka, Toshifumi Osaka, Satoshi Tsuneda   +6 more
doaj   +1 more source

Cervical Dystonia Is Associated With Aberrant Inhibitory Signaling Within the Thalamus

Frontiers in Neurology, 2021
Objective: The objective of this study is to investigate whether alterations in the neurotransmission of gamma-aminobutyric acid (GABA) in the thalamus are present in patients with cervical dystonia compared to healthy controls.Methods: GABA magnetic ...
Christopher L. Groth, Christopher L. Groth, Mark Brown, Justin M. Honce, Erika Shelton, Stefan H. Sillau, Brian D. Berman, Brian D. Berman, Brian D. Berman   +8 more
doaj   +1 more source

Synergistic Inhibition of Plantaricin E/F and Lactic Acid Against Aeromonas hydrophila LPL-1 Reveals the Novel Potential of Class IIb Bacteriocin

Frontiers in Microbiology, 2022
Plantaricin E/F (PlnEF) is a pair of two-component class IIb bacteriocin produced by lactic acid bacteria. PlnEF commonly displays potent antimicrobial activity against certain Gram-positive organisms.
Yang Wang, Yang Wang, Yunlu Wei, Yunlu Wei, Nan Shang, Nan Shang, Pinglan Li, Pinglan Li   +7 more
doaj   +1 more source

Naringin derivatives as glucosamine-6-phosphate synthase inhibitors based preservatives and their biological evaluation

Scientific Reports, 2020
Glucosamine-6-Phosphate synthase enzyme has been targeted for development of better and safe preservative due to its role in microbial cell wall synthesis.
Amit Lather, Sunil Sharma, Anurag Khatkar   +2 more
doaj   +1 more source

Suppression of Xanthomonas oryzae pv. oryzae biofilm formation by Acacia mangium methanol leaf extract [PDF]

Brazilian Journal of Biology, 2020
Xanthomonas oryzae pv. oryzae (Xoo), a pathogen responsible for rice bacterial leaf blight, produces biofilm to protect viable Xoo cells from antimicrobial agents.
S. N. Sarah Shafiei, K. Ahmad, N. F. M. Ikhsan, S. I. Ismail, K. Sijam   +4 more
doaj   +1 more source

Probiotic candidates among dairy Lactobacilli and Streptococcus thermophiles strains for control of the oral pathogen Porphyromonas gingivalis [PDF]

Folia Medica, 2021
Introduction: The gram-negative bacterium Porphyromonas gingivalis is a major causative agent of periodontitis in adults. It is also associated with disorders of the cardiovascular and endocrine systems, rheumatoid arthritis, pancreatic cancer, and ...
Michaela Michaylova, Tsvetelina Yungareva, Zoltan Urshev, Yana Dermendzieva, Blagovesta Yaneva, Iliyan Dobrev   +5 more
doaj   +3 more sources

Naringenin derivatives as glucosamine-6-phosphate synthase inhibitors: synthesis, antioxidants, antimicrobial, preservative efficacy, molecular docking and in silico ADMET analysis

BMC Chemistry, 2020
Background Preservatives have to be added in food, pharmaceuticals and cosmetics products to maintain their shelf life. However, the existing chemical based preservatives have been associated with severe side effects that compel the researchers to find ...
Amit Lather, Sunil Sharma, Anurag Khatkar   +2 more
doaj   +1 more source

Lead optimization for promising monoamine oxidase inhibitor from eugenol for the treatment of neurological disorder: synthesis and in silico based study

BMC Chemistry, 2019
Natural based inhibitors of monoamine oxidase are promising drug candidates for the treatment of several neurodegenerative and neuropsychological disorders including depression, anxiety, Parkinson’s disease and Alzheimer’s disease.
Priyanka Dhiman, Neelam Malik, Anurag Khatkar   +2 more
doaj   +1 more source

Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies

BMC Chemistry, 2020
Neurodegenerative disorders follow numerous pathological ways concerning overexpression of monoamine oxidase and formation of reactive oxygen species.
Priyanka Dhiman, Neelam Malik, Anurag Khatkar   +2 more
doaj   +1 more source