Results 131 to 140 of about 4,033,279 (373)
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
Creative Thinking and Dyscalculia: Conjectures About a Still Unexplored Link
Sara Magenes+3 more
doaj +1 more source
Emotion Potentiates Response Activation and Inhibition in Masked Priming
Previous studies have shown that emotion can have two-fold effects on perception. At the object-level, emotional stimuli benefit from a stimulus-specific boost in visual attention at the relative expense of competing stimuli. At the visual feature-level,
Bruno eBocanegra, Rene eZeelenberg
doaj +1 more source
Organophosphorus nerve agents and pesticides (Fig. 1) markedly increase the amount and duration of the action of acetylcholine at all of the synaptic sites where it acts, resulting in overstimulation of critical processes that can lead to incapacitation, muscle paralysis, and death. In a recent issue of PNAS, Albuquerque et al. (1) reported that a drug
openaire +3 more sources
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Glioblastoma multiforme (GBM) comprises several molecular subtypes, including proneural GBM. Most therapeutic approaches targeting glioma cells have failed.
S. Pyonteck+19 more
semanticscholar +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Inhibition has a central role in defining the selectivity of the responses of higher order neurons to sensory stimuli. However, the circuit mechanisms of regulation of these responses by inhibitory neurons are still unclear.
Liria Monica Masuda-Nakagawa+3 more
doaj +1 more source
Fine Discrimination of Analog Patterns by Nonlinear Dendritic Inhibition [PDF]
Recent experiments revealed that a certain class of inhibitory neurons in the cerebral cortex make synapses not onto cell bodies but at distal parts of dendrites of the target neurons, mediating highly nonlinear dendritic inhibition. We propose a novel form of competitive neural network model that realizes such dendritic inhibition.
arxiv
Notes on the formation and inhibition of mildew in paints [PDF]
Henry A. Gardner
openalex +1 more source
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source