Results 51 to 60 of about 6,364,217 (385)
Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition [PDF]
, 2018 The bile salt export pump (BSEP) is expressed at the canalicular domain of hepatocytes, where it mediates the elimination of monovalent bile salts into the bile.
Chen, Yuan +5 more
core +1 more source
Clinical Chemistry, 2019 Some old methods are still in use because they are simple and effective. One such method is the disk diffusion (or agar diffusion) test (1, 2). The diameter of the clear zone around an antibiotic-paper disk enables us to directly, and elegantly, visualize the inhibitory potency of an antibiotic. This test is …
openaire +4 more sources
Current Directions in Psychological Science, 2022 Inhibition is considered an essential process to goal pursuit and as a result has become a central construct in many disciplines in psychology and adjacent fields. Despite a century’s worth of debate, however, there is little consensus about what inhibition actually is.
Kaitlyn M. Werner +2 more
openaire +3 more sources
Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. [PDF]
, 2019 The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats.
Crawford, Elena +8 more
core +2 more sources
Molecules, 2020 Despite the development of targeted therapies in cancer, the problem of multidrug resistance (MDR) is still unsolved. Most patients with metastatic cancer die from MDR.
Henry Döring +3 more
doaj +1 more source
Genes & Development, 2007 The Hippo pathway plays a key role in organ size control by regulating cell proliferation and apoptosis in Drosophila. Although recent genetic studies have shown that the Hippo pathway is regulated by the NF2 and Fat tumor suppressors, the physiological ...
Bin Zhao +15 more
semanticscholar +1 more source
NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]
, 2011 Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Felmy, Felix +3 more
core +1 more source
Inhibiting the Inhibition: A Neuronal Network for Sound Localization in Reverberant Environments [PDF]
The Journal of Neuroscience, 2007 The precedence effect describes the phenomenon whereby echoes are spatially fused to the location of an initial sound by selectively suppressing the directional information of lagging sounds (echo suppression). Echo suppression is a prerequisite for faithful sound localization in natural environments but can break down depending on the behavioral ...
Pecka, Michael +8 more
openaire +3 more sources
Shaping Functional Architecture by Oscillatory Alpha Activity: Gating by Inhibition
Frontiers in Human Neuroscience, 2010 In order to understand the working brain as a network, it is essential to identify the mechanisms by which information is gated between regions. We here propose that information is gated by inhibiting task-irrelevant regions, thus routing information to ...
O. Jensen, A. Mazaheri
semanticscholar +1 more source
Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]
, 2018 Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre +10 more
core +2 more sources