Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Individual Differences in Inhibitory Control: A latent Variable Analysis
Inhibitory control represents a central component of executive functions and focuses on the ability to actively inhibit or delay a dominant response to achieve a goal. Although various tasks exist to measure inhibitory control, correlations between these
Anne Gärtner, A. Strobel
semanticscholar +1 more source
A mathematical model of human inhibitory control [PDF]
The Stop-Signal paradigm has generated a great deal of research interest among cognitive neuroscientists because of its ability to probe response inhibition [1]. In the task, subjects make a speeded button press when prompted, except on a fraction of trials where a second stimulus (the stop signal) instructs the subject to withold the prepotent ...
Joaquin A. Anguera+3 more
openaire +3 more sources
Noise-induced inhibitory suppression of malfunction neural oscillators [PDF]
Motivated by the aim to find new medical strategies to suppress undesirable neural synchronization we study the control of oscillations in a system of inhibitory coupled noisy oscillators.
A. A. Zaikin+13 more
core +2 more sources
The Effect of an Enriched Sport Program on Children’s Executive Functions: The ESA Program
PurposeThe effects of physical exercise on executive functions (EFs) are well-documented. EFs are involved in daily activities, and their development determines the quality of people’s future life, both in terms of mental health and quality of life.
Ambra Gentile+11 more
doaj +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Expression of CD226 is associated to but not required for NK cell education [PDF]
DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an activating receptor expressed on subsets of natural killer (NK) and T cells, interacts with its ligands CD155 or CD112, and has co-varied expression with inhibitory receptors. Since inhibitory
Bernhardt, Günter+9 more
core +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Got rhythm? Better inhibitory control is linked with more consistent drumming and enhanced neural tracking of the musical beat in adult percussionists and nonpercussionists [PDF]
Musical rhythm engages motor and reward circuitry that is important for cognitive control, and there is evidence for enhanced inhibitory control in musicians. We recently revealed an inhibitory control advantage in percussionists compared with vocalists,
Ashley, R.+3 more
core +1 more source
Bilingual Advantages in Inhibition or Selective Attention: More Challenges
A large sample (N = 141) of college students participated in both a conjunctive visual search task and an ambiguous figures task that have been used as tests of selective attention.
Kenneth R. Paap+4 more
doaj +1 more source