Results 91 to 100 of about 1,686,291 (300)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A unified framework for inhibitory control [PDF]

Trends in Cognitive Sciences, 2011
Inhibiting unwanted thoughts, actions and emotions figures centrally in daily life, and the prefrontal cortex (PFC) is widely viewed as a source of this inhibitory control. We argue that the function of the PFC is best understood in terms of representing and actively maintaining abstract information, such as goals, which produces two types of ...
Yuko, Munakata, Seth A, Herd, Christopher H, Chatham, Brendan E, Depue, Marie T, Banich, Randall C, O'Reilly   +5 more
openaire   +2 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

The association between music training and executive function in 6–7-year-old children

Frontiers in Education
Executive function development is especially important in the last year of the preschool period because this period precedes the transition to school.
Larisa Bayanova, Elena Chichinina, Margarita Aslanova, Margarita Aslanova   +3 more
doaj   +1 more source

A Systematic Review on the Influences of Neurotoxicological Xenobiotic Compounds on Inhibitory Control

Frontiers in Behavioral Neuroscience, 2019
Background: Impulsive and compulsive traits represent a variety of maladaptive behaviors defined by the difficulties to stop an improper response and the control of a repeated behavioral pattern without sensitivity to changing contingencies, respectively.
Cristian Perez-Fernandez, Pilar Flores, Fernando Sánchez-Santed   +2 more
doaj   +1 more source

Inhibitory Control: Mapping Medial Frontal Cortex [PDF]

Current Biology, 2017
Functional anatomy in frontal cortex has been elusive and controversial. A new study combines neuronal ensemble recordings and optogenetics to map a functional gradient in rodent prefrontal cortex that supports inhibitory control.
Nandakumar S, Narayanan, Mark, Laubach
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The Sensitivity and Psychometric Properties of a Brief Computer-Based Cognitive Screening Battery in a Depression Clinic [PDF]

, 2007
At present, there is poor accuracy in assessing cognitive and vegetative symptoms in depression using clinician or self-rated measures, suggesting the need for development of standardized tasks to assess these functions.
Berent, Stanley, Bieliauskas, Linas A., Caveney, Angela F., Giordani, Bruno, Kerber, Kevin, Langenecker, Scott Aaron, Marcus, Sheila, Mordhorst, Matthew J., Nielson, Kristy A., Rapport, Lisa J., Yodkovik, Naomi, Young, Elizabeth A., Zubieta, Jon-Kar   +12 more
core   +1 more source

Executive functions in insomnia disorder: a systematic review and exploratory meta-analysis [PDF]

, 2019
Background: Executive functions (EFs) are involved in the control of basic psychological processes such as attention and memory and also contribute to emotion regulation.
Aquino, Maria Raisa Jessica V., Ballesio, Andrea, Ferlazzo, Fabio, Kyle, Simon D., Lombardo, Caterina   +4 more
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source