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Therapeutic Potential Target of Adenosine for Epilepsy: Focusing on Its Interaction with the Molecular Epileptogenic Network. [PDF]

Biomolecules
Zhao X, Deng J, Xiong Z, Li T.
europepmc   +1 more source

Decoding the mechanisms of amyloid-β in synaptic toxicity. [PDF]

J Alzheimers Dis
Toruński P, Pizzirusso G, Winblad B, Arroyo-García LE.   +3 more
europepmc   +1 more source

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Phaclofen inhibition of the slow inhibitory postsynaptic potential in hippocampal slice cultures: A possible role for the GABAB-mediated inhibitory postsynaptic potential

Neuroscience, 1990
The GABAA antagonist bicuculline methiodide and the GABAB antagonist phaclofen were used to examine the function of the fast inhibitory postsynaptic potential and slow inhibitory postsynaptic potential, in hippocampal slice cultures in the rat. These cultures form easily-visualized monolayers of nerve cells which maintain the structure and synaptic ...
Alfred T Malouf, C A Robbins, Philip A Schwartzkroin   +2 more
exaly   +3 more sources

A dopaminergic inhibitory postsynaptic potential mediated by an increased potassium conductance

Neuroscience, 1989
Intracellular recordings from intact pituitary melanotrophs show that, in the same cell, inhibitory postsynaptic potentials resulting from either pituitary stalk stimulation or exogenous dopamine are abolished by D2 receptor antagonists, display identical conductance changes, are reversed in polarity at the same membrane potential and are sensitive to ...
Brian A Macvicar, Quentin J Pittman
exaly   +3 more sources

Valproate enhances inhibitory postsynaptic potentials in hippocampal neurons in vitro

Brain Research, 1987
Effects of sodium valproate (0.5-10 mM) on hippocampal cells (CA3 pyramidal cells and granule cells) of the guinea pig in vitro were studied by intra- and extracellular recording. Inhibitory postsynaptic potentials were markedly and reversibly augmented. Their shunting action as well as duration increased by more than 150%.
Marc L Zeise
exaly   +3 more sources

Inhibitory postsynaptic potentials evoked in hypoglossal motoneurons by lingual nerve stimulation

Experimental Neurology, 1982
Abstract The percent magnitude of a short- and a long-lasting inhibitory postsynaptic potential (IPSP) produced in tongue retractor and protruder motoneurons by lingual nerve stimulation was studied in cats. In the retractor motoneurons, stimulation of the ipsilateral lingual nerve produced primarily the short-lasting IPSP, and the neurons had ...
Mitsuru TAkata
exaly   +3 more sources

Inhibitory Postsynaptic Potentials in Grasshopper Muscle

Science, 1964
Hyperpolarizing inhibitory postsynaptic potentials have been discovered in fibers of the "jumping" muscle of the grasshopper. These potentials attenuate the depolarizing excitatory postsynaptic responses. They are enhanced during depolarization of the muscle fiber with applied current and are diminished and then reversed during hyperpolarization.
P N, USHERWOOD, H, GRUNDFEST
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Prolongation of hippocampal inhibitory postsynaptic potentials by barbiturates

Nature, 1975
IT is well documented that barbiturates dramatically prolong presynaptic inhibition1–4. Their effect on postsynaptic inhibition is less clear, although the available evidence suggests that a similar enhancement may occur at some sites5–7. Since the inhibitory postsynaptic potentials (i.p.s.p.s) in hippocampal neurones are unusually large and the ...
R A, Nicoll, J C, Eccles, T, Oshima, F, Rubia   +3 more
openaire   +2 more sources

Inhibitory postsynaptic potentials of hypoglossal motoneurons of the cat

Experimental Neurology, 1972
Abstract The hypoglossal nerve of the cat contains some afferent fibers, but the role of these afferents in controlling hypoglossal motoneuron activity has not yet been analyzed. The effect of hypoglossal nerve stimulation on activity of hypoglossal motoneurons was investigated using microelectrode technique.
T, Morimoto, Y, Kawamura
openaire   +2 more sources

Interneuronal barrages and ripple superposed on inhibitory postsynaptic potentials

Experientia, 1967
L'activite electrique des neurones du noyau thalamique ventro-lateral est etudiee ici chez des chats anesthesies au nembutal et immobilises avec du flaxedil au moyen d'un enregistrement intracellulaire. Nous avons observe que l'enregistrement de certains neurones montre que le potentiel nomme inhibiteur postsynaptique (IPSP) est accompagne de la ...
L A, Marco, T S, Brown, M E, Rouse
openaire   +2 more sources