Results 231 to 240 of about 71,654 (304)

Multiplexed changes in synaptic transmission underlie stress-induced reduction of persistent firing in the parietal cortex. [PDF]

Prog Neurobiol
Proddutur A, Rindner DJ, Azouz G, Beier KT, Lur G.   +4 more
europepmc   +1 more source

Noise‐induced reduction and early recovery of superior paraolivary nucleus sound‐offset responses

The Journal of Physiology, EarlyView.
Abstract figure legend Acoustic over‐exposure transiently disrupts auditory temporal processing in mouse superior paraolivary nucleus neurons. In control conditions, neurons exhibit robust sound‐offset (OFF) responses, which are abolished immediately following noise trauma, indicating impaired temporal encoding.
Mihai Stancu, Ezhilarasan Rajaram, Joseph A. Kroeger, Benedikt Grothe, Conny Kopp‐Scheinpflug   +4 more
wiley   +1 more source

3-Nitrotyrosine activates excitatory interneurons by inhibiting GABA receptors in the rat spinal dorsal horn. [PDF]

Pain Rep
Kaimochi Y, Yamanaka M, Taniguchi W, Nishio N, Matsuyama Y, Ueno T, Miyake R, Yamamoto Y, Nakatsuka T, Yamada H.   +9 more
europepmc   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, EarlyView.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source

Insular Somatostatin Interneurons Are Targeted by Motor Cortex Efferents and Modulate Affective States. [PDF]

Biol Psychiatry Glob Open Sci
Adank DN, Taylor A, Quan Y, Freels TG, Doyle MA, Luchsinger JR, Winder DG.   +6 more
europepmc   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Motor cortex directly excites the substantia nigra pars reticulata, the basal ganglia output nucleus. [PDF]

Nat Commun
Thompson WS, Wekwejt P, Grillner S, Silberberg G.   +3 more
europepmc   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source

Presynaptic chloride-dependent regulation of spontaneous glutamate release in the rat medial preoptic nucleus. [PDF]

Front Cell Neurosci
Pérez-Del-Pozo M, Kuznetsova T, Johansson S, Druzin M.   +3 more
europepmc   +1 more source

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway, Peter J. Ferrandi, Hector G. Paez, Christopher R. Pitzer, Junaith S. Mohamed, Michael R. Deschenes, James A. Carson   +6 more
wiley   +1 more source