Results 231 to 240 of about 107,392 (304)

The Role of Plasticity in Replay: Stability Through Anti‐Hebbian Rules

Hippocampus, Volume 36, Issue 3, May 2026.
ABSTRACT Hippocampal replay is now considered to be a cornerstone of memory consolidation, yet the synaptic plasticity rules governing its dynamics remain elusive. Under the standard asymmetric Hebbian spike‐timing dependent plasticity (STDP) model, the same spike patterns that promote activity propagation along one direction of sequential activation ...
Lior Baron, Kamran Diba, Asohan Amarasingham   +2 more
wiley   +1 more source

GluD1 at the synaptic crossroads: from domain structure to circuit dysfunction. [PDF]

Acta Pharmacol Sin
Chettiar PB, Dravid SM.
europepmc   +1 more source

Synaptic Potentiation in Hippocampus by eEF2K Inhibitor A484954

Hippocampus, Volume 36, Issue 3, May 2026.
ABSTRACT An important mechanism controlling protein synthesis is through phosphorylation of the eukaryotic elongation factor 2 (eEF2) by its kinase eEF2K. Hyperphosphorylation of eEF2 is linked to many neuronal diseases characterized by cognitive impairments.
Qian Yang, Tian Li, Hannah M. Jester, Qiang Su, Xueyan Zhou, Alexey G. Ryazanov, Tao Ma   +6 more
wiley   +1 more source

Impaired excitability of fast-spiking neurons in a novel mouse model of <i>KCNC1</i> epileptic encephalopathy. [PDF]

Elife
Wengert ER, Liebergall SR, Jimenez T, Cheng MA, Markwalter KH, Clatot J, Hong Y, Arias L, Marsh ED, Zhang X, Tsetsenis T, Somarowthu A, Akizu N, Goldberg EM.   +13 more
europepmc   +1 more source

Micro‐Stimulation Timing Framed Around an Averaged Theta Period of Stimulation Determines Hippocampal Recruitment in Cued Fear Conditioning

Hippocampus, Volume 36, Issue 3, May 2026.
ABSTRACT The importance of precise timing of neuronal activity, relative to ongoing slower oscillations, is reshaping the engram theory and our understanding of how memories are encoded and stored. The hippocampal theta‐wave phase‐encoding of neuronal firing predicts behavioral outcomes and cognitive performance in memory tasks.
Paula Gonçalves Vieira Teixeira, Leonardo de Oliveira Guarnieri, Grace Schenatto Pereira, Márcio Flávio Dutra Moraes   +3 more
wiley   +1 more source

Neuronal Calcium Signaling and Cytoskeletal Dynamics in Neurodegeneration. [PDF]

Int J Mol Sci
Rakovskaya A, Volkova E, Pchitskaya E.
europepmc   +1 more source

A Narrative Review of Synaptic Transmission and Its Role in Neurological and Psychiatric Disorders: A Molecular Perspective. [PDF]

Cureus
Ahmed N, Rather HJ, Rana A, Vasim KA, Thaker KR, Tripathi D.   +5 more
europepmc   +1 more source

Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex. [PDF]

Cereb Cortex
Vattino LG, Clayton KK, Hackett TA, Polley DB, Takesian AE.   +4 more
europepmc   +1 more source

Inhibitory inputs from thalamus promote resilient spiking in tail of striatum. [PDF]

iScience
Haetzel LM, Gründemann J.
europepmc   +1 more source

Age-dependent increases in dorsal hippocampal postsynaptic α5GABA-a receptors may be lost in a rat model of Alzheimer's disease. [PDF]

Sci Rep
George JC, Tipton AE, Bonfa NVS, Farb DH, Russek SJ.   +4 more
europepmc   +1 more source