Results 231 to 240 of about 108,180 (299)

Mitochondrial alterations as potential early events in neuromuscular junction remodelling with muscle disuse

Experimental Physiology, EarlyView.
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova, Evgenii Lysenko, Fabio Sarto, Mladen Gasparini, Boštjan Šimunic, Rado Pišot, Marco V. Narici   +6 more
wiley   +1 more source

Synaptic transmission in supragranular layers of the human cortex - comparative review of structure, function, and plasticity. [PDF]

Front Synaptic Neurosci
Eichler A, Kruse P, Schob C, Lenz M.
europepmc   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Redox-Activated Probes Enable High-Contrast Live Imaging of Native Postsynaptic Scaffolds. [PDF]

Angew Chem Int Ed Engl
Huhn C, Mille C, Ho SY, Lützenkirchen F, Khayenko V, Hein M, Werner C, Kneussel M, Hell JW, Specht CG, Maric HM.   +10 more
europepmc   +1 more source

NMDA and glycine receptors provide dual presynaptic regulation on climbing fibre inputs to cerebellar Purkinje cells

The Journal of Physiology, EarlyView.
Abstract figure legend Vibrodissociated Pukinje neurons retain active synaptic connections, including those from adhering fragments of the climbing fibre. These fragments generate excitatory synaptic events and the frequency of these events is increased by exposure to either NMDA [with d‐serine (d‐ser) as a co‐agonist] or glycine at a high (100 µM ...
David C. H. Benton, Alan D. Robertson, Matthew Caldwell, Yuriy Pankratov, Lema Imam, Trevor G. Smart, Gareth Morris, Guy W. J. Moss   +7 more
wiley   +1 more source

Synaptic plasticity in the perforant pathway drives inhibitory reorganization enhancing dentate gyrus functionality. [PDF]

iScience
Estarellas C, Álvarez-Salvado E, Pérez-Cervera L, Caramés JM, Pérez-Montoyo E, López-Madrona VJ, Garcia-Hernandez R, Mirasso CR, Canals S.   +8 more
europepmc   +1 more source

Amacrine cell inputs to OFF midget ganglion cells in macaque retina

The Journal of Physiology, EarlyView.
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak, Andrea S. Bordt, Emma R. Yang, Joel N. Yearick, Marcus Mazzaferri, James A. Kuchenbecker, Judith Mosinger Ogilvie, Sara S. Patterson, Jay Neitz   +8 more
wiley   +1 more source

Brain networking pain and anxiety: From basic mechanism to future treatment. [PDF]

Mol Pain
Zhuo M.
europepmc   +1 more source

Propofol regulates arousal by enhancing inhibitory synaptic transmission of noradrenergic neurons in the locus coeruleus of adult male mice. [PDF]

Sci Rep
Abe T, Kurabe M, Nakamura Y, Sasaki M, Seino Y, Furutani K, Ueno M, Baba H.   +7 more
europepmc   +1 more source

Liquid-liquid phase separation in neural development. [PDF]

Cell Mol Life Sci
Surini S, de Curtis I.
europepmc   +1 more source