Results 31 to 40 of about 602,951 (277)
Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain
Cell Reports, 2023 Summary: Neuropathic pain is a debilitating condition resulting from damage to the nervous system. Imbalance of spinal excitation and inhibition has been proposed to contribute to neuropathic pain.
Noosha Yousefpour +9 more
doaj +1 more source
iScience, 2023 Summary: Synaptic inhibition is critical for controlling neuronal excitability and function. During global cerebral ischemia (GCI), inhibitory synapses are rapidly eliminated, causing hyper-excitability which contributes to cell-death and the ...
Joshua D. Garcia +7 more
doaj +1 more source
THE FINE STRUCTURE OF INHIBITORY SYNAPSES IN THE CRAYFISH [PDF]
The Journal of Cell Biology, 1961 Physiological investigations have shown that the synaptic input to the sensory neuron of the stretch receptor in the abdominal muscles of the crayfish is purely inhibitory. This neuron was chosen, therefore, as a site in which to study the fine structure of inhibitory synaptic endings.
R P, PETERSON, F, PEPE
openaire +2 more sources
Diurnal rhythms in neurexins transcripts and inhibitory/excitatory synapse scaffold proteins in the biological clock [PDF]
, 2012 The neurexin genes (NRXN1/2/3) encode two families (α and β) of highly polymorphic presynaptic proteins that are involved in excitatory/inhibitory synaptic balance.
Hendricks, Michael +15 more
core +2 more sources
SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling
Cell Reports, 2019 Summary: GABAA receptors mediate fast inhibitory transmission in the brain, and their number can be rapidly up- or downregulated to alter synaptic strength.
Els F. Halff +3 more
doaj +1 more source
Excitatory and inhibitory synapse reorganization immediately after critical sensory experience in a vocal learner. [PDF]
Elife, 2018 Excitatory and inhibitory synapses are the brain’s most abundant synapse types. However, little is known about their formation during critical periods of motor skill learning, when sensory experience defines a motor target that animals strive to imitate.
Huang Z +4 more
europepmc +2 more sources
Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse [PDF]
, 2002 Receptor-ligand couples in the cell-cell contact interface between a T cell and an antigen-presenting cell form distinct geometric patterns and undergo spatial rearrangement within the contact interface.
Nigel John Burroughs +3 more
core +1 more source
PLoS ONE, 2013 Associative fear learning, resulting from whisker stimulation paired with application of a mild electric shock to the tail in a classical conditioning paradigm, changes the motor behavior of mice and modifies the cortical functional representation of ...
Malgorzata Jasinska +5 more
doaj +1 more source
Long-term plasticity at inhibitory synapses [PDF]
Current Opinion in Neurobiology, 2011 Experience-dependent modifications of neural circuits and function are believed to heavily depend on changes in synaptic efficacy such as LTP/LTD. Hence, much effort has been devoted to elucidating the mechanisms underlying these forms of synaptic plasticity.
Pablo E, Castillo +2 more
openaire +2 more sources
Inhibitory Synapses Get Madd for Neuroligin [PDF]
Neuron, 2015 The mechanisms mediating the appropriate clustering of neurotransmitter receptors opposite release sites are poorly understood. Two studies in this issue of Neuron, Maro et al. (2015) and Tu et al. (2015), identify a new extracellular effector for neuroligin in GABAergic postsynaptic differentiation.
Zhang, Peng, Craig, Ann Marie
openaire +2 more sources