Results 141 to 150 of about 1,635,352 (355)

On the initial mass function and the fragmentation of molecular clouds

open access: yesMonthly Notices of the Royal Astronomical Society, 1983
n ...
F. FERRINI   +2 more
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Investigations of Massive Filaments and Star Formation (INFANT). I. Core Identification and Core Mass Function

open access: yesThe Astrophysical Journal
Filamentary structures are ubiquitously found in high-mass star-forming clouds. To investigate the relationship between filaments and star formation, we carry out the INFANT (Investigations of Massive Filaments and Sar Formation) survey, a multiscale ...
Yu Cheng   +18 more
doaj   +1 more source

The Initial Mass Function of Stars

open access: yes, 2006
Observations and theory of the IMF are briefly reviewed. Slight variations have been observed, although they are difficult to prove unambiguously. Most detailed theoretical models reproduce the IMF, but because they use different assumptions and conditions, there is no real convergence of explanations yet.
openaire   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

First Detection of CO Isotopologues in a High-redshift Main-sequence Galaxy: Evidence of a Top-heavy Stellar Initial Mass Function

open access: yesThe Astrophysical Journal
Recent observations and theories have presented a strong challenge to the universality of the stellar initial mass function (IMF) in extreme environments. A notable example has been found for starburst conditions, where evidence favors a top-heavy IMF, i.
Ziyi Guo   +7 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

The Initial Mass Function of Stars and Brown Dwarfs in the Upper Sco Association

open access: yesThe Astronomical Journal
I present infrared spectroscopy of 37 brown dwarf candidates in the Upper Scorpius (Upper Sco) association, 35 of which are classified as young and cool, making them likely members.
K. L. Luhman
doaj   +1 more source

The Stellar Initial Mass Function in The Galactic Center [PDF]

open access: yes, 2007
Massive stars define the upper limits of the star formation process, dominate the energetics of their local environs, and significantly affect the chemical evolution of galaxies. Their role in starburst galaxies and the early Universe is likely to be important, but we still do not know the maximum mass that a star can possess, i.e.``the upper mass ...
openaire   +3 more sources

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