Results 61 to 70 of about 15,924,839 (382)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Numerical Investigation of Influence of In-Situ Stress Ratio, Injection Rate and Fluid Viscosity on Hydraulic Fracture Propagation Using a Distinct Element Approach

Energies, 2016
Numerical simulation is very useful for understanding the hydraulic fracturing mechanism. In this paper, we simulate the hydraulic fracturing using the distinct element approach, to investigate the effect of some critical parameters on hydraulic ...
Bo Zhang, Xiao Li, Zhaobin Zhang, Yanfang Wu, Yusong Wu, Yu Wang   +5 more
doaj   +1 more source

A novel method for the quantitative characterization of the simultaneous plasticizing and filling performance in ultrasonic plasticization micro injection molding

Materials & Design, 2021
A novel method is proposed for the quantitative characterization of the unique simultaneous plasticizing and filling phenomenon in ultrasonic plasticization micro-injection molding (UPMIM). The injection rate is redefined as the mass flow rate during the
Yang Zou, Wangqing Wu, Xiaotian Zhou, Guomeng Wei, Bingyan Jiang   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Burning rate control of solid propellants Patent [PDF]

, 1967
Pressurized gas injection for burning rate control of solid ...
Heidmann, M. F., Povinelli, L. A.
core   +1 more source

A Model for Tracking Fronts of Stress-Induced Permeability Enhancement

, 2013
Using an analogy to the classical Stefan problem, we construct evolution equations for the fluid pore pressure on both sides of a propagating stress-induced damage front.
Karra, Satish, Kelkar, Sharad, Lewis, K. C.   +2 more
core   +1 more source

A zero-dimensional model to simulate injection rate from first generation common rail diesel injectors under thermodynamic diagnosis

Energy, 2018
The injection rate curve is an important input parameter in the thermodynamic diagnosis and in the predictive models, and it can also be used to simulate fuel sprays under different operating conditions.
J. A. Soriano, C. Mata, O. Armas, C. Ávila   +3 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

OPTIMIZATION OF THE FORMATION ACID FRACTURING AT THE FACILITIES OF OJSC «TATNEFT»

Известия высших учебных заведений: Нефть и газ, 2015
The authors analyzed the process parameters of the formation acid hydraulic fracturing (FAHF) operations performing taking into account the additional production achieved.
I. I. Mannanov, L. I. Garipova
doaj   +1 more source

Transport of ferrihydrite nanoparticles in saturated porous media: role of ionic strength and flow rate [PDF]

, 2012
The use of nanoscale ferrihydrite particles, which are known to effectively enhance microbial degradation of a wide range of contaminants, represents a promising technology for in situ remediation of contaminated aquifers.
Bosch, J., Meckenstock, R., Sethi, Rajandrea, Tosco, Tiziana Anna Elisabetta   +3 more
core   +1 more source