Results 101 to 110 of about 26,569 (289)

Vacancy defect‐induced electron homing breaks phosphodiester bonds for RNA depletion‐driven cancer therapy

open access: yesBMEMat, EarlyView.
Illustration of 5% S‐vacancy Bi2S3 mediated phosphodiester bonds cleavage in RNA of hepatocellular carcinoma cells, which suppressing ERI3 expression, inhibiting cell proliferation and promoting apoptosis. Abstract Genome‐wide hypertranscription is a hallmark of malignant progression.
Chuncheng Yang   +12 more
wiley   +1 more source

Perbandingan Visual Analog Score antara Teknik Injeksi Air Steril Intrakutan Satu Titik dan Empat Titik untuk Mengurangi Nyeri Persalinan Spontan

open access: yesJurnal Anestesi Perioperatif, 2014
Almost one third of women suffer from continuous lower back pain during labour. Therefore, the aim of this study was to compare the effectivity between single and four injections in reducing labour pain measured by visual analogue scale (VAS).
Faisal Rosady   +2 more
doaj   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović   +11 more
wiley   +1 more source

Mycobacterium Bovis (Strain BCG) Effects on the Growth and Metastasis of a Transplantable Hamster Lung Adenocarcinoma [PDF]

open access: yes, 1979
Author Institution: Department of Microbiology, and Comprehensive Cancer Center, The Ohio State UniversityThe effect of Bacillus-Calmette-Guerin (BCG) on the growth of an adenocarcinoma of the lung induced in a Syrian hamster was evaluated.
Bakaletz, Alan P., Zwilling, Bruce S.
core  

Intradermal injections through hollow microneedles

open access: yes, 2018
Hollow microneedles are a promising alternative to conventional drug delivery techniques such as oral drug administration and hypodermic injections, and are used for delivering drugs and therapeutics into the skin. Although the benefits of intradermal drug delivery have been known for decades, our understanding of fluid absorption by skin tissue has ...
openaire   +1 more source

Fournier's Gangrene Associated with Intradermal Injection of Cocaine

open access: yesThe Journal of Sexual Medicine, 2013
ABSTRACT Introduction Cocaine abuse is associated with a number of medical complications, most notably arrhythmias, myocardial infarction, and cerebral hemorrhages. The injection of cocaine in the penis has been predominantly recorded into the corpus cavernosae and is associated with priapism.
Fahd, Khan   +6 more
openaire   +2 more sources

Spontaneous regression of equine sarcoids is an exceptional event

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley   +1 more source

Safety evaluation of a buffer used in the lyophilization of canine platelets: type I hypersensitivity reaction in dogs caused by bovine serum albumin

open access: yesFrontiers in Veterinary Science
IntroductionThe present study was designed to evaluate the safety of substances generally used in the preparation of lyophilized platelet products (LPPs) because the possibility of an immune response to bovine serum albumin (BSA) was considered high when
Hee-Jae Choi   +3 more
doaj   +1 more source

Effects of motherwort alkaloids on rat ear acne

open access: yesBangladesh Journal of Pharmacology, 2016
The aim of this study was to explore the effects of motherwort alkaloids on rat ear acne. The rats that were administered high, medium, and low doses of motherwort alkaloids, tanshinone capsules, a model and a control group.
Miao Mingsan   +6 more
doaj   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye   +3 more
wiley   +1 more source

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