Results 81 to 90 of about 26,569 (289)

Injection-site reactions upon Kineret (anakinra) administration: experiences and explanations [PDF]

open access: yes, 2011
Anakinra (Kineret), a recombinant form of human interleukin-1 (IL-1) receptor antagonist, is approved for the treatment of rheumatoid arthritis (RA) in combination with methotrexate.
Christina Kaiser   +6 more
core   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

Effects of Intradermal Botulinum Toxin Injections on Herpes Zoster Related Neuralgia

open access: yesInfection and Drug Resistance, 2023
Fen Peng,1 Tian-Bao Xia2 1Department of Dermatology, Peking University Third Hospital, Beijing, People’s Republic of China; 2Department of Dermatology, People’s Liberation Army Strategic Support Force Characteristic Medical Center, Beijing, People’s ...
Peng F, Xia TB
doaj  

Lymphatic Abnormalities in Noonan Syndrome Extend Beyond Clinically Apparent Disease

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Lymphatic disease represents a well‐described manifestation of Noonan syndrome (NS), yet the full phenotypic spectrum remains incompletely characterized, especially in asymptomatic individuals. We conducted a cross‐sectional study including 10 individuals with NS (four with peripheral lymphedema and six without) and 10 age‐ and sex‐matched ...
Inger Norlyk Sheyanth   +7 more
wiley   +1 more source

Clinical characteristics of monkeypox vaccine injection site reactions: A cohort of seven patients

open access: yesJEADV Clinical Practice
Background Monkeypox (Mpox) infections are considered a public health emergency, prompting the need for the administration of a preventative vaccine to high‐risk individuals.
Anthony A. Gaspari
doaj   +1 more source

Platelet-rich plasma combined with intralesional triamcinolone acetonide for the treatment of alopecia areata: A case report

open access: yesJournal of Dermatology and Dermatologic Surgery, 2016
Treatment of long standing alopecia areata can be extremely difficult. Combining more than one treatment modality may be needed. Promising results have been previously reported using platelet-rich plasma.
Thamer Mubki
doaj   +1 more source

Penicillin Allergy Assessment and Skin Testing in the Outpatient Setting [PDF]

open access: yes, 2019
Penicillin allergies are among of the most commonly reported allergies, yet only 10% of these patients are truly allergic. This leads to potential inadvertent negative consequences for patients and makes treatment decisions challenging for clinicians ...
Avery, Lisa M.   +3 more
core   +3 more sources

Hyperalgesia to heat after intradermal injection of capsaicin

open access: yesBrain Research, 1987
Capsaicin injected intradermally into the human forearm lowered the pain threshold for heat at the injection site. Both the magnitude and duration of hyperalgesia were dose dependent over the range of 0.1-100 micrograms, given in a constant volume of 10 microliter. Thus, capsaicin may be a useful tool in studies of the neural mechanisms of hyperalgesia.
D A, Simone   +3 more
openaire   +2 more sources

Establishment of a mouse model of propylthiouracil‐induced antineutrophil cytoplasmic antibody‐associated vasculitis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda   +9 more
wiley   +1 more source

Different therapeutic modalities in a patient with multiple spontaneously developed keloids: a case report [PDF]

open access: yes, 2006
Keloids are benign tumors that usually develop as an excessive healing response to injury. They remain a challenging therapeutic problem to this day. Numerous treatment approaches are available, yet therapeutic results are often not satisfactory.
Bukvić-Mokos, Zrinka   +2 more
core  

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