Results 1 to 10 of about 153,401 (288)

Erythropoietin Protective Role Against Methotrexate Testicular Adverse Effects [PDF]

International Journal of Biomedicine, 2023
Background: The adverse effects of cytotoxic medications like methotrexate, particularly reproductive damage reported in the numerous experimental studies, limit their effectiveness as anticancer therapies. The current study's objectives were to identify
Ali Hassan A. Ali, Turki Rfaa Alotaibi, Talal Hani Abdullah Arab, Ahmad Hamad Zaila, Bader Musaed Alharbi, Ziyad Saud Alharbi, Abdullah Mohammed Alduhaymi, Abdulaziz Fahad Alamer, Fahad Abdullah Alquraini, Nawaf Khalid Alzmami, Talal A. Alharbi, Abdulrahman Omar Alkhurayyif, Nawaf Oqab N Alotaibi, Arif Mohammed M Alanazi, Abdulaziz Mohammed A Alasiri   +14 more
doaj   +1 more source

Intraperitoneal Injection of Neonatal Mice

BIO-PROTOCOL, 2023
Administration of substances into neonatal mice is required for early treatment with pre-clinical therapeutics, delivery of recombination-inducing substances, and dosing with viruses or toxins, amongst other things. Several injection routes into mouse pups are possible, including intravenous and intracerebroventricular, each with their own advantages ...
Pocratsky, Amanda M, Sleigh, James N
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THE INTRAPERITONEAL INJECTION OF SALINE SOLUTION [PDF]

Archives of Pediatrics & Adolescent Medicine, 1918
The parenteral administration of water is a widely used therapeutic measure in the treatment of the severe nutritional disorders of infants, especially when, after continued vomiting and diarrhea, marked loss of body fluids has resulted. It is an efficacious means of combating this serious complication.
Kenneth F. Maxcy, Kenneth D. Blackfan
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Ketamine Inhalation Alters Behavior and Lower Urinary Tract Function in Mice

Biomedicines, 2022
We aimed to evaluate behavioral and lower urinary tract changes in mice using a novel ketamine inhalation model mimicking human ketamine abusers and compare the results to those obtained using a ketamine intraperitoneal injection model.
Shu-Yu Wu, Chun-Kai Hsu, Li-Yi Lim, Yi-Chyan Chen, Hsi-Hsien Chang, Stephen Shei-Dei Yang   +5 more
doaj   +1 more source

Intraperitoneal Injection of Mice [PDF]

Applied Microbiology, 1969
Steward, Ornellas, Beernink, and Northway (2) reported a 14% error in the placement of intraperitoneal injections of mice. They considered this error inherent in the technique and not simply correctable. We similarly found an error in the intraperitoneal injection of mice and attempted to identify the cause of error by varying such technical procedures
Jacqueline Koehler, Laura Greenaway, Norman A. Miner   +2 more
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Intraperitoneal Injection into Adult Zebrafish [PDF]

Journal of Visualized Experiments, 2010
A convenient method for chemically treating zebrafish is to introduce the reagent into the tank water, where it will be taken up by the fish. However, this method makes it difficult to know how much reagent is absorbed or taken up per fish. Some experimental questions, particularly those related to metabolic studies, may be better addressed by ...
Louis H. Philipson, Stefani C. Eames, Mary D. Kinkel, Victoria E. Prince   +3 more
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A prototype single-port device for pressurized intraperitoneal aerosol chemotherapy. Technical feasibility and local drug distribution [PDF]

Acta Cirúrgica Brasileira, 2017
Purpose: To evaluate the technical feasibility and homogeneity of drug distribution of pressurized intraperitoneal aerosol chemotherapy (PIPAC) based on a novel process of intraperitoneal drug application (multidirectional aerosolization).
Rafael Seitenfus, Paulo Roberto Walter Ferreira, Gabriel Oliveira dos Santos, Rafael José Vargas Alves, Antonio Nocchi Kalil, Eduardo Dipp de Barros, Olivier Glehen, Thaís Andrade Costa Casagrande, Eduardo Aimoré Bonin, Edison Martins da Silva Junior   +9 more
doaj   +1 more source

Assessment of mouse VEGF neutralization by ranibizumab and aflibercept.

PLoS ONE, 2022
PurposeTo assess the interaction between ranibizumab, aflibercept, and mouse vascular endothelial growth factor (VEGF), both in vivo and in vitro.MethodsIn vivo, the effect of intravitreal injection of ranibizumab and aflibercept on oxygen induced ...
Yusuke Ichiyama, Riko Matsumoto, Shumpei Obata, Osamu Sawada, Yoshitsugu Saishin, Masashi Kakinoki, Tomoko Sawada, Masahito Ohji   +7 more
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Development of a Supramolecular Hydrogel for Intraperitoneal Injections

Macromolecular Bioscience, 2023
AbstractLocal intraperitoneal drug administration is considered a challenging drug delivery route. The therapeutic efficiency is low, mainly due to rapid clearance of drugs. To increase the intraperitoneal retention time of specific drugs, a pH‐sensitive supramolecular hydrogel that can act as a drug delivery vehicle is developed.
Anne G. W. E. Wintjens, Peter‐Paul K. H. Fransen, Kaatje Lenaerts, Hong Liu, Geert C. van Almen, Sebastiaan van Steensel, Marion J. Gijbels, Ignace H. J. T. de Hingh, Patricia Y. W. Dankers, Nicole D. Bouvy   +9 more
openaire   +3 more sources

Comparing the Histopathological Effects of Selenium Nanoparticles and Selenium Nanocomposites in Rat Models [PDF]

Disease and Diagnosis, 2021
Background: Selenium nanoparticles (Se NPs) and selenium nanocomposites (Se NCs) have different biological effects. The current study aimed to compare the effects of newly synthesized Se NPs and Se NCs on biochemical and histopathological parameters of ...
Mohammad Reza Hajinezhad, Abbas Jamshidian, Motahareh Abdollahi, Alireza Samzadeh Kermani   +3 more
doaj   +1 more source