Results 111 to 120 of about 3,110,551 (267)
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Preprint: Artemisinin inhibits innate immune cell chemotaxis, cytokine production and NET release
, 2022 Immune cell chemotaxis to the sites of pathogen invasion is critical for fighting infection, but in life-threatening conditions such as sepsis and Covid-19, excess activation of the innate immune system is thought to cause a damaging invasion of immune ...
Vilar, B. +7 more
core +1 more source
Discovering adaptive features of innate immune memory
Immunological ReviewsSummaryConventionally, it was thought that innate immunity operated through a simple system of nonspecific responses to an insult. However, this perspective now seems overly simplistic. It has become evident that intricate cooperation and networking among various cells, receptors, signaling pathways, and protein complexes are essential for regulating ...
Mina Sadeghi, Maziar Divangahi
openaire +2 more sources
Hematopoietic stem cell state and fate in trained immunity
Cell Communication and SignalingTrained immunity serves as a de facto memory for innate immune responses, resulting in long-term functional reprogramming of innate immune cells. It enhances resistance to pathogens and augments immunosurveillance under physiological conditions.
Weinian Liao +3 more
doaj +1 more source
Advanced Materials, EarlyView.Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song +8 more
wiley +1 more source
Innate immune memory in fibroblasts [PDF]
, 2018 The innate immune system is a generic response to infection or injury. Evidence shows the innate response has immunological memory capable of altering subsequent responses to stimuli.
Crowley, Thomas
core +4 more sources
Frontiers in ImmunologyThe immune memory is one of the defensive strategies developed by both unicellular and multicellular organisms for ensuring their integrity and functionality.
Diana Boraschi +7 more
doaj +1 more source
Information Transmission Strategies for Self‐Organized Robotic Aggregation
Advanced Robotics Research, EarlyView.In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng +5 more
wiley +1 more source
The role of natural killer cells in adaptive immune responses [PDF]
Human natural killer (NK) cells have been shown to respond to numerous pathogenic stimuli, producing IFN-y as well as cytolytic effector molecules such as perforin and granzymes.
Horowitz, Amir
core +1 more source
Potential Role of Gut Microbiota in Induction and Regulation of Innate Immune Memory
Frontiers in Immunology, 2019 The gut microbiota significantly regulates the development and function of the innate and adaptive immune system. The attribute of immunological memory has long been linked only with adaptive immunity.
Shikha Negi +8 more
doaj +1 more source