Results 201 to 210 of about 3,110,551 (267)

Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence. [PDF]

PLoS Pathog
Korša A, Baur M, Schulz NKE, Anaya-Rojas JM, Mellmann A, Kurtz J.   +5 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Hematopoietic stem cell a reservoir of innate immune memory. [PDF]

Front Immunol
Ruffinatto L, Groult Y, Iacono J, Sarrazin S, de Laval B.   +4 more
europepmc   +1 more source

Programmable Information Processing With Reconfigurable Self‐Contact Variable Stiffness Mechanical Metamaterial

Advanced Science, EarlyView.
Reconfigurable self‐contact variable stiffness metamaterials based on shape memory polymers enable programmable stiffness switching. Static arrays store and encrypt information with immunity to electromagnetic interference, while asymmetric stiffness converts symmetric vibration into directional matter transport.
Huadong Qin, Wenyu Zhu, Xin Wang, Cheng Shen, Li Cheng, Tian Jian Lu, Terence Xiaoteng Liu, Han Meng   +7 more
wiley   +1 more source

Protocol for measuring endogenous 24(S),25-epoxycholesterol and inducing innate immune memory in mouse macrophages. [PDF]

STAR Protoc
Liu Y, Jin H, Huo B, Xia X, Liu J.
europepmc   +1 more source

Multi‐Dimensional Physical‐Layer Security via Digitally Mediated Space–Time Modulation

Advanced Science, EarlyView.
Digitally mediated space–time modulation moves radiation control beyond hardware‐bound switching. Multiple information‐bearing and masking waveforms are jointly synthesized at baseband and coherently coupled to simple periodic time modulation, enabling programmable, independently directed multi‐beam radiation without increasing switching‐state ...
Kejin Chen, Heng Mao, Feng Yang, Gengbo Wu, Lei Zhang, Yikai Chen, Shi‐Wei Qu, Jun Hu, Shiwen Yang   +8 more
wiley   +1 more source

Blurring: Clue to Earthworm Innate Immune Memory?

Frontiers in Microbiology, 2016
Edwin eCooper
doaj   +1 more source

<i>Salmonella</i> LVR01 triggers antagonistic two-armed innate immune memory that impacts on antitumor efficacy. [PDF]

Front Immunol
Chilibroste S, Dos Santos JC, Mónaco A, Joosten LAB, Moreno M, Chabalgoity JA.   +5 more
europepmc   +1 more source

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source

BCG-derived acellular membrane vesicles elicit antimycobacterial immunity and innate immune memory. [PDF]

Front Immunol
Yamaguchi T, Samukawa N, Matsumoto S, Shiota M, Matsumoto M, Nakao R, Hirayama S, Yoshida Y, Nishiyama A, Ozeki Y, Tomita S.   +10 more
europepmc   +1 more source