Results 131 to 140 of about 1,083,097 (291)

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors

, 2000
Adrian Ozinsky, David M. Underhill, Jason D. Fontenot, Adeline M. Hajjar, Kelly D. Smith, Christopher B. Wilson, Lea Schroeder, Alan Aderem   +7 more
openalex   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

The Interactions of Peptides with the Innate Immune System Studied with Use of T7 Phage Peptide Display

, 2000
Alex V. Sokoloff, Guofeng Zhang, Magdolna G. Sebestyén, Jon A. Wolff, Ildikó Bock   +4 more
openalex   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

The role of dendritic cells in the innate immune system

, 2000
Georgina J. Clark, Nicola Angel, Masato Kato, J. Alejandro López, Kelli P. A. MacDonald, Slavica Vučković, Derek N.J. Hart   +6 more
openalex   +1 more source

Skin: an active component of the fetal innate immune system [PDF]

, 2003
Yeon Mee Kim, Gi Jin Kim, Mee‐Ran Kim, Tinnakorn Chaiworapongsa, Jimmy Espinoza, Bo Ruem Yoon, Emmanuel Bujold, Roberto Romero   +7 more
openalex   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source

Genomic investigation of innate sensing pathways in the tumor microenvironment

BMC Cancer
The innate immune system is the first responder to infectious agents, cellular debris, and cancerous growths. This system plays critical roles in the antitumor immune responses by boosting and priming T cell-mediated cytotoxicity but is understudied due ...
Gabriella Quinn, Gianna Maggiore, Bo Li
doaj   +1 more source

Prolonged suppression of the innate immune system in the horse following an 80 km endurance race [PDF]

, 2003
Paula J. Robson, Tesha Alston, Kathryn H. Myburgh   +2 more
openalex   +1 more source

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

Advanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma, Qihang Ding, Yue Wang, Zhiwei Zhang, Yuding Zhang, Hui Shi, Lintao Cai, Ping Gong, Pengfei Zhang, Zhen Cheng, Jong Seung Kim   +10 more
wiley   +1 more source