Hygiene hypothesis and innate immunity. evaluating the role of environmental factors and genetic polymorphisms on the expression of receptors of the innate immune system [PDF]
, 2009 Background In ‘westernised’ countries, the prevalence of childhood asthma and allergy has risen throughout the last few decades. A series of epidemiological studies showed reduced prevalence of asthma and allergy among farmers’ children compared to non ...
Bieli, Christian
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Biochemical and functional studies on mouse ficolin-B, a novel pattern recognition molecule of the innate immune system [PDF]
, 2011 Ficolins are members of the collectin family of proteins which in human and mice are able to recognize pathogen associated molecular patterns (PAMPs) on microbial surfaces.
Elumalai, Preetham
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Determinants of innate immune responses to mycobacteria [PDF]
, 2012 Includes bibliographical references.Innate cells such as macrophages, monocytes, myeloid dendritic cells and granulocytes recognise mycobacteria and initiate immune responses such as phagocytosis, cytokine production and expression of maturation markers.
Shey, Muki Shehu
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Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes [PDF]
, 2013 Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the
Cols, M +5 more
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Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia
Frontiers in Cardiovascular Medicine, 2015 The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds +2 more
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Virulence, 2021 Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate ...
Jinlong Wan +4 more
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Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation
Mediators of Inflammation, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
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Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges
Frontiers in Immunology, 2017 The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
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Immunomodulation of Innate Immune Cells
, 2020 Activation of innate immune system underlies both pathological and physiological inflammatory responses and is critical for the host. Regulated innate immune response is thus essential not only for the elimination of invading pathogens but also for the ...
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Regulation of Adaptive Immunity by the Innate Immune System [PDF]
Science, 2010 Twenty years after the proposal that pattern recognition receptors detect invasion by microbial pathogens, the field of immunology has witnessed several discoveries that have elucidated receptors and signaling pathways of microbial recognition systems and how they control the generation of T and B lymphocyte–mediated immune responses.
Akiko, Iwasaki, Ruslan, Medzhitov
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