Results 201 to 210 of about 1,512,579 (348)

The Interplay Between Therapeutic Self-Amplifying RNA and the Innate Immune System: Balancing Efficiency and Reactogenicity. [PDF]

Int J Mol Sci
Kunyk D, Plotnikova M, Bespalov M, Shevyrev D, Klotchenko S, Ivanov R, Reshetnikov V.   +6 more
europepmc   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

The ADAMTS2 metalloproteinase inhibits tumor growth by regulating the innate immune system. [PDF]

Cancer Cell Int
Joannes L, Dupont L, Stock L, Arpigny E, Hubert P, Ancion M, Luyckx M, Abinet J, Peng W, Calaldo D, Noel A, Marichal T, Herfs M, Deroanne C, Colige A.   +14 more
europepmc   +1 more source

Evolution of adaptive immunity from transposable elements combined with innate immune systems

, 2014
Eugene V. Koonin, Mart Krupovìč
openalex   +2 more sources

Ontogenesis of the secretory immune system and innate defence factors in human parotid glands [PDF]

, 1991
PerS Thrane, T. O. Rognum, P Brandtzæg
openalex   +1 more source

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

Penaeus monodon fibrinogen-related lectin interacts with lipopolysaccharide and β-1,3-glucan binding protein to activate the innate immune system. [PDF]

Biochem J
Wilasluck P, Sukonthamarn P, Tassanakajon A, Wangkanont K.   +3 more
europepmc   +1 more source

Editorial: The contribution of viruses and innate immune system in the pathogenesis of type 1 diabetes. [PDF]

Front Endocrinol (Lausanne), 2023
Nigi L, Laiho JE, Hyöty H, Dotta F.
europepmc   +1 more source

The Effects of Tolerance on Allograft Damage Caused by the Innate Immune System

, 2008
Ruediger Hoerbelt, Christopher L. Benjamin, Tsuyoshi Shoji, Stuart L. Houser, Ashok Muniappan, R.S Hasse, Levi Ledgerwood, James S. Allan, David H. Sachs, Joren C. Madsen   +9 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source