Results 91 to 100 of about 2,416,042 (300)

Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae [PDF]

open access: yes, 2007
The physiological functions of the acute phase protein serum amyloid P (SAP) component are not well defined, although they are likely to be important, as no natural state of SAP deficiency has been reported.
Botto, M.   +3 more
core  

“Cruising together”—ASC specks and SAA, a perfect match in chronic inflammation

open access: yesEMBO Molecular Medicine
Currently, over 350 million people worldwide live with chronic inflammatory diseases, facing a range of complications that severely impact their quality of life.
Salie Maasewerd   +1 more
doaj   +1 more source

Bile Acids Activated Receptors Regulate Innate Immunity

open access: yesFrontiers in Immunology, 2018
Once known exclusively for their role in nutrients absorption, primary bile acids, chenodeoxycholic and cholic acid, and secondary bile acids, deoxycholic and lithocholic acid, are signaling molecules, generated from cholesterol breakdown by the ...
S. Fiorucci   +3 more
semanticscholar   +1 more source

Innate immunity: the first line of defense against SARS-CoV-2

open access: yesNature Immunology, 2022
M. Diamond, T. Kanneganti
semanticscholar   +1 more source

Cell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factors [PDF]

open access: yes, 2011
It has been known for some time that retroviruses can disseminate between immune cells either by conventional cell-free transmission or by directed cell-to-cell spread.
Albin   +120 more
core   +2 more sources

Innate immunity and HCV

open access: yesJournal of Hepatology, 2013
Hepatitis C virus (HCV) infections become chronic in the majority of infected individuals, and chronic hepatitis C (CHC) can lead to cirrhosis and hepatocellular carcinoma. The innate immune system is central to host-virus interactions during the entire natural course of the disease.
openaire   +4 more sources

Disruption of myelin structure and oligodendrocyte maturation in a macaque model of congenital Zika infection

open access: yesNature Communications
Zika virus (ZikV) infection during pregnancy can cause congenital Zika syndrome (CZS) and neurodevelopmental delay in infants, of which the pathogenesis remains poorly understood.
Jennifer Tisoncik-Go   +15 more
doaj   +1 more source

Do synovial biopsies help to support evidence for involvement of innate immunity in the immunopathology of Behçet's disease? [PDF]

open access: yes, 2009
Behçet's disease is a complex vasculitis of unknown etiology. Abundant neutrophils suggest the involvement of innate immunity. Cytokines are skewed to the T-helper-1 pattern.
Daele, P.L.A. (Paul) van   +3 more
core   +1 more source

Innate immunity and adjuvants [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2011
Innate immunity was for a long time considered to be non-specific because the major function of this system is to digest pathogens and present antigens to the cells involved in acquired immunity. However, recent studies have shown that innate immunity is not non-specific, but is instead sufficiently specific to discriminate self from pathogens through ...
openaire   +3 more sources

A Th2 Cytokine Profile in Appendicular Lavage Fluid Suggests Allergy as a Possible Etiology for Acute Appendicitis

open access: yesMediators of Inflammation, 2019
Acute appendicitis is the most frequent surgical abdominal emergency, but its etiology remains poorly understood. Histological examination of the appendix, following its removal due to acute appendicitis, consistently shows features in common with ...
Nuno Carvalho   +8 more
doaj   +1 more source

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