Results 111 to 120 of about 738,107 (298)

Molecular insights on the proangiogenic effects of VEGF like growth factor derived from horseshoe crab perivitelline fluid

Scientific Reports
The current study investigated the proangiogenic effects of fraction VII of perivitelline fluid (hscPVF-VEGF) obtained from the late-stage embryos of Indian horseshoe crab (Tachypleus gigas; Müller) using human umbilical cord tissue-derived MSCs (hUCMSCs)
K. G. Aghila Rani, Hrishikesh Pandit, Rambhadur Subedi, Sayli Otiv-Pandit, Anil Bankati Jogdand, Hajra Gupta, Prayagraj Fandilolu, Sushama Rokade, Susan Idicula-Thomas, Anil Chatterji, Taruna Madan   +10 more
doaj   +1 more source

Interferon Lambda Genetics and Biology in Regulation of Viral Control

Frontiers in Immunology, 2017
Type III interferons, also known as interferon lambdas (IFNλs), are the most recent addition to the IFN family following their discovery in 2003. Initially, IFNλ was demonstrated to induce expression of interferon-stimulated genes and exert antiviral ...
Emily A. Hemann, Michael Gale, Ram Savan
doaj   +1 more source

Major components of fish immunity: a review [PDF]

, 2016
Fish are fascinating creatures with a certain degree of immunity comparable to those of mammals. The fish's immune system consists of two major components, innate and adaptive immunities.
Nawi, Mohd Firdaus, Saad, Mohd Zamri
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Unlocking the potential for microbiome‐based therapeutics to address the sustainable development goal of good health and wellbeing

Microbial Biotechnology
Recent years have witnessed major advances and an ever‐growing list of healthcare applications for microbiome‐based therapeutics. However, these advances have disproportionately targeted diseases common in high‐income countries (HICs).
Emily L. Gulliver, Sara K. Di Simone, Michelle Chonwerawong, Samuel C. Forster   +3 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Innate immunity [PDF]

Current Biology, 1998
R Alan, B Ezekowitz, Jules Hoffmann
openaire   +3 more sources

Innate Immunity

Journal of Pediatric Gastroenterology and Nutrition, 2005
Alan Aderem, Elena A. Levashina
openaire   +4 more sources

Dissecting Cell Death Pathways in Influenza A Virus Infection: Comparative Insights from Human Models

Viruses
Influenza A virus remains a major global health threat, causing annual epidemics and occasional pandemics. Programmed cell death, including apoptosis, pyroptosis, and necroptosis, with emerging evidence for ferroptosis, plays a dual role in influenza ...
Ngoc Mai Khoi Nguyen, Alison C. West, Rebecca L. Ambrose, Michelle D. Tate   +3 more
doaj   +1 more source

Pathogen Response Genes Mediate Caenorhabditis elegans Innate Immunity

, 2012
Innate immunity is crucial in the response and defense against pathogens for invertebrates and vertebrates alike. The soil nematode Caenorhabditis elegans is a useful model to study the eukaryotic innate immune response to microbial pathogenesis.
Anthony, Hannah L.
core