Results 161 to 170 of about 358,690 (312)

KLF feedback loops in innate immunity. [PDF]

Front Immunol
Salmon JM, Adams H, Magor GW, Perkins AC.   +3 more
europepmc   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source

C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response [PDF]

, 2000
Debra Gershov, SunJung Kim, Nathan Brot, Keith B. Elkon   +3 more
openalex   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

A single entomopathogenic nematode infection assay for Drosophila melanogaster larvae

MethodsX
The entomopathogenic nematodes (EPNs) Steinernema carpocapsae and Steinernema hermaphroditum can efficiently infect the fruit fly, Drosophila melanogaster.
Sreeradha Mallick, Eric Kenney, Jacob Rashap, Ioannis Eleftherianos   +3 more
doaj  

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors

, 2000
Adrian Ozinsky, David M. Underhill, Jason D. Fontenot, Adeline M. Hajjar, Kelly D. Smith, Christopher B. Wilson, Lea Schroeder, Alan Aderem   +7 more
openalex   +1 more source

Essential Role for the dsRNA-Dependent Protein Kinase PKR in Innate Immunity to Viral Infection [PDF]

, 2000
Siddharth Balachandran, Paul C. Roberts, Laura E Brown, Ha Truong, Asit K. Pattnaik, David R. Archer, Glen N. Barber   +6 more
openalex   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

Editorial: Cell death in innate immunity and inflammatory diseases. [PDF]

Front Immunol
Pizzuto M, Cipollina C.
europepmc   +1 more source

The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes [PDF]

, 2000
Takashi Nishimura, Hidemitsu Kitamura, Kenji Iwakabe, Takashi Yahata, Akio Ohta, M. Sato, Kazuyoshi Takeda, Ko Okumura, Luc Van Kaer, Tetsu Kawano, M. Taniguchi, Minoru Nakui, Masashi Sekimoto, Toshiaki Koda   +13 more
openalex   +1 more source