Results 161 to 170 of about 730,043 (275)

Editorial: Role of endogenous regulators of innate immunity in sepsis. [PDF]

Front Immunol
Wang H, Meng X, Tang D, Yao Y.
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Innate Immunity in the Cottonmouth Watersnake (<i>Agkistrodon piscivorus</i>). [PDF]

Animals (Basel)
Merchant M, Epperson J, Baker S.
europepmc   +1 more source

Genetic Analysis of Plant Innate Immunity [PDF]

, 2011
Lu, Xunli
core  

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

ADAR1-Mediated RNA Editing Regulates Innate Immunity in Pulmonary Hypertension. [PDF]

Circ Res
Shen Y, Bisserier M.
europepmc   +1 more source

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

The Intrinsic Innate Immunity of Hepatocytes Suppresses HBV Replication and Is Antagonized by HBx. [PDF]

Viruses
Zeng C, Megahed FAK, Guo Y, Sun D, Wang Y, Liu Q, Bi Y, Li J, Zhou Q, Xie Q, Sun P, Zhou X.   +11 more
europepmc   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Recent insights into the role of innate immunity in lupus. [PDF]

Hum Mol Genet
Robinson LA, Pascual V.
europepmc   +1 more source