Innate Immunity and Neuroinflammation [PDF]
Mediators of Inflammation, 2013 Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful.
Abhishek Shastri +2 more
openaire +9 more sources
'Towards a Conceptual Framework for Innate Immunity' [PDF]
, 2005 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core +5 more sources
Early Interferon-γ Production in Human Lymphocyte Subsets in Response to Nontyphoidal Salmonella Demonstrates Inherent Capacity in Innate Cells [PDF]
, 2010 Background Nontyphoidal Salmonellae frequently cause life-threatening bacteremia in sub-Saharan Africa. Young children and HIV-infected adults are particularly susceptible.
Anna E. Seeley +5 more
core +9 more sources
libtissue - implementing innate immunity [PDF]
, 2006 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
core +3 more sources
The evolution of resistance through costly acquired immunity [PDF]
, 2004 We examine the evolutionary dynamics of resistance to parasites through acquired immunity. Resistance can be achieved through the innate mechanisms of avoidance of infection and reduced pathogenicity once infected, through recovery from infection and ...
Boots M., Michael Boots, Roger G. Bowers
core +2 more sources
In vivo detection of lamellocytes in Drosophila melanogaster. [PDF]
, 2009 Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific ...
Brand +17 more
core +1 more source
Integrative Genomics Reveals the Genetics and Evolution of the Honey Bee’s Social Immune System [PDF]
, 2019 Social organisms combat pathogens through individual innate immune responses or through social immunity—behaviors among individuals that limit pathogen transmission within groups.
Currie, Rob +12 more
core +1 more source
A functional DC cross talk promotes human ILC homeostasis in humanized mice
Blood Advances, 2017 : Humanized mice harboring human hematopoietic systems offer a valuable small-animal model to assess human immune responses to infection, inflammation, and cancer.
Silvia Lopez-Lastra +8 more
doaj +1 more source
The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans
Nature Communications, 2020 lncRNAs are transcriptional regulators, but little is known of them functioning as negative feedback regulators of inflammation in humans. Here, the authors show that the human lncRNA LUCAT1 sequesters STAT1 to limit JAK/STAT signaling and the ...
Shiuli Agarwal +7 more
doaj +1 more source
HIV and innate immunity ? a genomics perspective [PDF]
, 2013 Innate immunity is a theme of increasing interest for HIV research. However, the term is overstretched to cover biological barriers, cellular systems, soluble factors, signaling pathways, and effectors and is inconsistently applied.
McLaren, P.J., Rausell, A., Telenti, A.
core +4 more sources