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Inner ear barriers to nanomedicine-augmented drug delivery and imaging
There are several challenges to inner ear drug delivery and imaging due to the existence of tight biological barriers to the target structure and the dense bone surrounding it. Advances in imaging and nanomedicine may provide knowledge for overcoming the
Jing Zou, Ilmari Pyykkö, Jari Hyttinen
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The diagnostics of inner ear diseases are primarily functional, but there is a growing interest in inner ear biomarkers. The present scoping review aimed to elucidate gaps in the literature regarding the definition, classification system, and an overview
Nahla A. Gomaa+4 more
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Inner ear morphology in the Atlantic molly Poecilia mexicana [PDF]
Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Hess, Martin+2 more
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Proteomics and the Inner Ear [PDF]
The inner ear, one of the most complex organs, contains within its bony shell three sensory systems, the evolutionary oldest gravity receptor system, the three semicircular canals for the detection of angular acceleration, and the auditory system ‐ unrivaled in sensitivity and frequency discrimination.
openaire +3 more sources
Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture. [PDF]
Stem cell-derived inner ear sensory epithelia are a promising source of tissues for treating patients with hearing loss and dizziness. We recently demonstrated how to generate inner ear sensory epithelia, designated as inner ear organoids, from mouse ...
Rachel E DeJonge+5 more
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Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce+7 more
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Development of a dynamic virtual reality model of the inner ear sensory system as a learning and demonstrating tool [PDF]
In order to keep track of the position and motion of our body in space, nature has given us a fascinating and very ingenious organ, the inner ear. Each inner ear includes five biological sensors - three angular and two linear accelerometers - which ...
Gourinat, Yves+2 more
core +3 more sources
Optimising the parameters of cochlear implant imaging with cone-beam computed tomography [PDF]
With computed tomography (CT), the delicate structures of the inner ear may be hard to visualise, which a cochlear implant (CI) electrode array can further complicate.
Aarnisalo, Antti+5 more
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Current strategies for drug delivery to the inner ear
For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery ...
Hongzhuo Liu, Jinsong Hao, Kevin S. Li
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Nanoparticles in Inner Ear Diseases
Nanoparticles are novel discoveries which hold a promising role for delivering medications into the inner ear in the future. Nanoparticles are formed by the preparation of different biomaterials.
Soumick Ranjan Sahoo
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