Results 41 to 50 of about 842,718 (302)
Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing. [PDF]
, 2015 Balance disequilibrium is a significant contributor to falls in the elderly. The most common cause of balance dysfunction is loss of sensory cells from the vestibular sensory epithelia of the inner ear.
Daniel J. Jagger +38 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2019 Hair cells are specialized mechanosensitive cells responsible for mediating balance and hearing within the inner ear. In mammals, hair cells are limited in number and do not regenerate.
Cristiana Mattei +14 more
doaj +1 more source
Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography [PDF]
Clinical and Experimental Otorhinolaryngology, 2020 Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic ...
Se-Joon Oh +5 more
doaj +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss
Frontiers in Pharmacology, 2014 Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
doaj +1 more source
NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss
Frontiers in Cell and Developmental Biology, 2022 The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of ...
Francis Rousset +8 more
doaj +1 more source
Planning of tunnel-based robotic access to the inner ear [PDF]
, 2021 A new planning strategy for tunnel-based robotic access to the inner ear is proposed based on the study of three- dimensional models of the middle and inner ear anatomy.
O'Toole Bom Braga, Gabriela +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang +11 more
wiley +1 more source
Assessment of drug permeability through an ex vivo porcine round window membrane model
iScience, 2023 Summary: Delivery of pharmaceutical therapeutics to the inner ear to treat and prevent hearing loss is challenging. Systemic delivery is not effective as only a small fraction of the therapeutic agent reaches the inner ear.
Adele Moatti +9 more
doaj +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source