Results 21 to 30 of about 80,529 (260)

Proteomics and the Inner Ear [PDF]

open access: yesDisease Markers, 2001
The inner ear, one of the most complex organs, contains within its bony shell three sensory systems, the evolutionary oldest gravity receptor system, the three semicircular canals for the detection of angular acceleration, and the auditory system ‐ unrivaled in sensitivity and frequency discrimination.
openaire   +2 more sources

Inner ear barriers to nanomedicine-augmented drug delivery and imaging

open access: yesJournal of Otology, 2016
There are several challenges to inner ear drug delivery and imaging due to the existence of tight biological barriers to the target structure and the dense bone surrounding it. Advances in imaging and nanomedicine may provide knowledge for overcoming the
Jing Zou, Ilmari Pyykkö, Jari Hyttinen
doaj   +1 more source

Biomarkers for Inner Ear Disorders: Scoping Review on the Role of Biomarkers in Hearing and Balance Disorders

open access: yesDiagnostics, 2020
The diagnostics of inner ear diseases are primarily functional, but there is a growing interest in inner ear biomarkers. The present scoping review aimed to elucidate gaps in the literature regarding the definition, classification system, and an overview
Nahla A. Gomaa   +4 more
doaj   +1 more source

Development of the inner ear [PDF]

open access: yesCurrent Opinion in Genetics & Development, 2015
The vertebrate inner ear is a sensory organ of exquisite design and sensitivity. It responds to sound, gravity and movement, serving both auditory (hearing) and vestibular (balance) functions. Almost all cell types of the inner ear, including sensory hair cells, sensory neurons, secretory cells and supporting cells, derive from the otic placode, one of
openaire   +3 more sources

Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells

open access: yesBiomedicines, 2021
Zebrafish is an excellent model for exploring the development of the inner ear. Its inner ear has similar functions to that of humans, specifically in the maintenance of hearing and balance. Mafba is a component of the Maf transcription factor family. It
Xiang Chen   +10 more
doaj   +1 more source

Congenital Inner Ear Abnormalities and COVID-19-Related Ear Infections

open access: yesEar, Nose & Throat Journal, 2022
Congenital deformities of the labyrinth of the inner ear may be associated with an increased risk of infection and varying degrees of otologic and vestibular dysfunction. Lateral semicircular canal abnormalities specifically can be associated with either
Shivesh Maharaj MBBCH, MMED, FCORL   +1 more
doaj   +1 more source

Nanoparticles in Inner Ear Diseases

open access: yesNational Board of Examinations Journal of Medical Sciences, 2023
Nanoparticles are novel discoveries which hold a promising role for delivering medications into the inner ear in the future. Nanoparticles are formed by the preparation of different biomaterials.
Soumick Ranjan Sahoo
doaj   +1 more source

Inner ear immunology

open access: yesAmerican Journal of Otolaryngology, 1985
Previously the authors proposed that the perilymphatic inner ear immune system is independent of that of the cerebrospinal fluid. In the present study, the effect of dilatation of blood vessels surrounding the cochlea of chinchillas on the transfer of serum antibodies to the perilymph was tested. The possibility of local production of antibodies in the
Kawauchi, H.   +3 more
openaire   +2 more sources

Visualization of macrophage subsets in the development of the fetal human inner ear

open access: yesFrontiers in Immunology, 2022
BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic trauma or
Claudia Steinacher   +11 more
doaj   +1 more source

Potential application value of pigment epithelium-derived factor in sensorineural hearing loss

open access: yesFrontiers in Neuroscience, 2023
The inner ear is a complex and precise auditory perception system responsible for receiving and converting sound signals into neural signals, enabling us to perceive and understand sound.
Zihui Sun   +12 more
doaj   +1 more source

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