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Zebrafish is an excellent model for exploring the development of the inner ear. Its inner ear has similar functions to that of humans, specifically in the maintenance of hearing and balance. Mafba is a component of the Maf transcription factor family. It
Xiang Chen +10 more
doaj +1 more source
Visualization of macrophage subsets in the development of the fetal human inner ear
BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic trauma or
Claudia Steinacher +11 more
doaj +1 more source
Congenital Inner Ear Abnormalities and COVID-19-Related Ear Infections
Congenital deformities of the labyrinth of the inner ear may be associated with an increased risk of infection and varying degrees of otologic and vestibular dysfunction. Lateral semicircular canal abnormalities specifically can be associated with either
Shivesh Maharaj MBBCH, MMED, FCORL +1 more
doaj +1 more source
Potential application value of pigment epithelium-derived factor in sensorineural hearing loss
The inner ear is a complex and precise auditory perception system responsible for receiving and converting sound signals into neural signals, enabling us to perceive and understand sound.
Zihui Sun +12 more
doaj +1 more source
Nanoparticles in Inner Ear Diseases
Nanoparticles are novel discoveries which hold a promising role for delivering medications into the inner ear in the future. Nanoparticles are formed by the preparation of different biomaterials.
Soumick Ranjan Sahoo
doaj +1 more source
Autophagy in the Vertebrate Inner Ear [PDF]
Autophagy is a conserved catabolic process that results in the lysosomal degradation of cell components. During development, autophagy is associated with tissue and organ remodeling, and under physiological conditions it is tightly regulated as it plays a housekeeping role in removing misfolded proteins and damaged organelles.
Marta Magariños +9 more
openaire +5 more sources
Characterization of the Usher Syndrome gene CDH23: implications for mechanosensation in the vertebrate inner ear [PDF]
Deafness is the most common form of sensory impairment afflicting the human population. Approximately one in eight hundred children is born with serious hearing impairment and more than half of these cases are likely due to single gene defects.
Siemens, Jan-Erik
core +1 more source
Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration
Liposome nanocarriers (LPNs) are potentially the future of inner ear therapy due to their high drug loading capacity and efficient uptake in the inner ear after a minimally invasive intratympanic administration.
Jing Zou +4 more
doaj +1 more source
Molecular biology of hearing [PDF]
The inner ear is our most sensitive sensory organ and can be subdivided into three functional units: organ of Corti, stria vascularis and spiral ganglion.
Diensthuber, M +3 more
core +1 more source
Background Treatment of inner ear diseases remains a problem because of limited passage through the blood-inner ear barriers and lack of control with the delivery of treatment agents by intravenous or oral administration. As a minimally-invasive approach,
Kinnunen Paavo KJ +6 more
doaj +1 more source

