Results 31 to 40 of about 1,559,915 (394)

Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells

open access: yesBiomedicines, 2021
Zebrafish is an excellent model for exploring the development of the inner ear. Its inner ear has similar functions to that of humans, specifically in the maintenance of hearing and balance. Mafba is a component of the Maf transcription factor family. It
Xiang Chen   +10 more
doaj   +1 more source

The endocranial morphology and inner ear of the abelisaurid theropod Aucasaurus garridoi [PDF]

open access: yes, 2015
A partial cranial endocast and right inner ear of the Cretaceous abelisaurid dinosaur Aucasaurus garridoi were digitally reconstructed from CT scans.
Paulina Carabajal, Ariana   +1 more
core   +1 more source

Current strategies for drug delivery to the inner ear

open access: yesActa Pharmaceutica Sinica B, 2013
For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery ...
Hongzhuo Liu, Jinsong Hao, Kevin S. Li
doaj   +1 more source

Visualization of macrophage subsets in the development of the fetal human inner ear

open access: yesFrontiers in Immunology, 2022
BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic trauma or
Claudia Steinacher   +11 more
doaj   +1 more source

The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15 [PDF]

open access: yes, 2006
Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different elements of the hair bundle, the stereocilia and a kinocilium, are interconnected by a variety of link
Ahmed, Zubair M   +14 more
core   +2 more sources

Effects of Glucocorticoids on the Inner Ear [PDF]

open access: yesFrontiers in Surgery, 2021
Hypothesis: Recently, several lines of evidence have suggested that the inner ear is under hormonal control. It is likely that steroids have some influence on the inner ear.Background: Many clinicians have been empirically using steroids for the treatment of diseases associated with endolymphatic hydrops. The theoretical grounds for this are not clear,
Setsuko Takeda   +2 more
openaire   +4 more sources

NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss

open access: yesFrontiers in Cell and Developmental Biology, 2022
The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of ...
Francis Rousset   +8 more
doaj   +1 more source

Molecular and functional characterization of gap junctions in the avian inner ear. [PDF]

open access: yes, 2006
To analyze the fundamental role of gap junctions in the vertebrate inner ear, we examined molecular and functional characteristics of gap junctional communication (GJC) in the auditory and vestibular system of the chicken.
Becker, D, Forge, A, Nickel, R
core   +1 more source

Potential application value of pigment epithelium-derived factor in sensorineural hearing loss

open access: yesFrontiers in Neuroscience, 2023
The inner ear is a complex and precise auditory perception system responsible for receiving and converting sound signals into neural signals, enabling us to perceive and understand sound.
Zihui Sun   +12 more
doaj   +1 more source

AAV-ie enables safe and efficient gene transfer to inner ear cells

open access: yesNature Communications, 2019
Hearing loss is the most common sensory disorder. While gene therapy has emerged as a promising treatment of inherited diseases like hearing loss, it is dependent on the identification of gene delivery vectors.
Fangzhi Tan   +16 more
semanticscholar   +1 more source

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