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Zebrafish is an excellent model for exploring the development of the inner ear. Its inner ear has similar functions to that of humans, specifically in the maintenance of hearing and balance. Mafba is a component of the Maf transcription factor family. It
Xiang Chen+10 more
doaj +1 more source
The endocranial morphology and inner ear of the abelisaurid theropod Aucasaurus garridoi [PDF]
A partial cranial endocast and right inner ear of the Cretaceous abelisaurid dinosaur Aucasaurus garridoi were digitally reconstructed from CT scans.
Paulina Carabajal, Ariana+1 more
core +1 more source
Current strategies for drug delivery to the inner ear
For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery ...
Hongzhuo Liu, Jinsong Hao, Kevin S. Li
doaj +1 more source
Visualization of macrophage subsets in the development of the fetal human inner ear
BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic trauma or
Claudia Steinacher+11 more
doaj +1 more source
The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15 [PDF]
Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different elements of the hair bundle, the stereocilia and a kinocilium, are interconnected by a variety of link
Ahmed, Zubair M+14 more
core +2 more sources
Effects of Glucocorticoids on the Inner Ear [PDF]
Hypothesis: Recently, several lines of evidence have suggested that the inner ear is under hormonal control. It is likely that steroids have some influence on the inner ear.Background: Many clinicians have been empirically using steroids for the treatment of diseases associated with endolymphatic hydrops. The theoretical grounds for this are not clear,
Setsuko Takeda+2 more
openaire +4 more sources
NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss
The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of ...
Francis Rousset+8 more
doaj +1 more source
Molecular and functional characterization of gap junctions in the avian inner ear. [PDF]
To analyze the fundamental role of gap junctions in the vertebrate inner ear, we examined molecular and functional characteristics of gap junctional communication (GJC) in the auditory and vestibular system of the chicken.
Becker, D, Forge, A, Nickel, R
core +1 more source
Potential application value of pigment epithelium-derived factor in sensorineural hearing loss
The inner ear is a complex and precise auditory perception system responsible for receiving and converting sound signals into neural signals, enabling us to perceive and understand sound.
Zihui Sun+12 more
doaj +1 more source
AAV-ie enables safe and efficient gene transfer to inner ear cells
Hearing loss is the most common sensory disorder. While gene therapy has emerged as a promising treatment of inherited diseases like hearing loss, it is dependent on the identification of gene delivery vectors.
Fangzhi Tan+16 more
semanticscholar +1 more source