Results 31 to 40 of about 447,391 (302)

Asymmetrically severe internal auditory canal hypoplasia: A case report. [PDF]

open access: yes, 2020
We present a case of an otherwise healthy 20-month-old with congenital sensorineural hearing loss. CT and MR imaging demonstrated bilateral asymmetrically severe hypoplasia of the internal auditory canals and vestibulocochlear nerves.
Djalilian, Hamid R   +6 more
core   +1 more source

NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss

open access: yesFrontiers in Cell and Developmental Biology, 2022
The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of ...
Francis Rousset   +8 more
doaj   +1 more source

Round window membrane and delivery of biologically active agents into the cochlea [PDF]

open access: yes, 2010
Establishing efficient methods for local administration of drugs to the inner ear has great clinical relevance for the management of inner ear disorders. However, the administration route remains a critical issue.
Saber, Amanj K.
core   +1 more source

Multimodal Atlas of the Murine Inner Ear: From Embryo to Adult

open access: yesFrontiers in Neurology, 2021
The inner ear is a complex organ housed within the petrous bone of the skull. Its intimate relationship with the brain enables the transmission of auditory and vestibular signals via cranial nerves.
Jean-Paul Bryant   +15 more
doaj   +1 more source

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

open access: yes, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura   +6 more
core   +2 more sources

Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies

open access: yesBalkan Medical Journal, 2019
Inner ear anomalies diagnosed using a radiological study are detected in almost 30% of cases with congenital or prelingual-onset sensorineural hearing loss.
Emre Ocak, Duygu Duman, Mustafa Tekin
doaj   +1 more source

Otitis media impacts hundreds of mouse middle and inner ear genes. [PDF]

open access: yesPLoS ONE, 2013
Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken.
Carol J MacArthur   +4 more
doaj   +1 more source

Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2020
Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic ...
Se-Joon Oh   +5 more
doaj   +1 more source

Precision medicine: a new era for inner ear diseases

open access: yesFrontiers in Pharmacology
The inner ear is the organ responsible for hearing and balance. Inner ear dysfunction can be the result of infection, trauma, ototoxic drugs, genetic mutation or predisposition. Often, like for Ménière disease, the cause is unknown.
Elisa Tavazzani   +8 more
doaj   +1 more source

Generation of Vestibular Tissue-Like Organoids From Human Pluripotent Stem Cells Using the Rotary Cell Culture System

open access: yesFrontiers in Cell and Developmental Biology, 2019
Hair cells are specialized mechanosensitive cells responsible for mediating balance and hearing within the inner ear. In mammals, hair cells are limited in number and do not regenerate.
Cristiana Mattei   +14 more
doaj   +1 more source

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