Results 41 to 50 of about 453,570 (346)
Frontiers in Cell and Developmental Biology, 2019 Hair cells are specialized mechanosensitive cells responsible for mediating balance and hearing within the inner ear. In mammals, hair cells are limited in number and do not regenerate.
Cristiana Mattei +14 more
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Inner ear‐specific autoantibodies [PDF]
The Laryngoscope, 1993 AbstractThe sera of patients with idiopathic sensorineural hearing loss (SNHL) were examined, using qualitative immunoblotting (Western blotting), for the presence of inner ear (IE)‐specific autoantibodies. The water‐soluble extracts and the sodium dodecyl sulfate‐soluble extracts were prepared as the antigens from bovine IE tissues and several other ...
S, Yamanobe, J P, Harris
openaire +3 more sources
Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss
Frontiers in Pharmacology, 2014 Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
doaj +1 more source
Assessment of drug permeability through an ex vivo porcine round window membrane model
iScience, 2023 Summary: Delivery of pharmaceutical therapeutics to the inner ear to treat and prevent hearing loss is challenging. Systemic delivery is not effective as only a small fraction of the therapeutic agent reaches the inner ear.
Adele Moatti +9 more
doaj +1 more source
Application of Nanomedicine in Inner Ear Diseases
Frontiers in Bioengineering and Biotechnology, 2022 The treatment of inner ear disorders always remains a challenge for researchers. The presence of various physiological barriers, primarily the blood–labyrinth barrier (BLB), limits the accessibility of the inner ear and hinders the efficacy of various ...
Qianyu Lin +12 more
doaj +1 more source
Vestibular schwannoma and ipsilateral endolymphatic hydrops: an unusual association [PDF]
, 2017 Vestibular schwannoma and endolymphatic hydrops are two conditions that may present with similar audio-vestibular symptoms. The association of the two in the same patient represents an unusual nding that may lead clinicians to errors and delays in ...
ALTISSIMI, Giancarlo +8 more
core +2 more sources
Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Determining the Location of GABA Receptor mRNA Transcripts in \u3cem\u3eDanio rerio\u3c/em\u3e [PDF]
, 2018 -aminobutyric acid (GABA) is a neurotransmitter that has been shown to be present in the inner ear. GABA binds to two classes of GABA receptors (GABARs): GABAARs are pentameric ion channels (isoforms include: 1-6, β 1-3, 1-3, 1-3, , , and ); GABABRs ...
O\u27Keefe, Jack
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Systemic lupus erythematosus and hearing disorders: literature review and meta-analysis of clinical and temporal bone findings [PDF]
, 2017 Objective: This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE).
DI STADIO, Arianna, Ralli, Massimo
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Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source