Results 41 to 50 of about 447,391 (302)
Frontiers in NeuroscienceHearing loss is the most common sensory disorder in human beings. Cochlear sensory cells are the basis of hearing. Cochlear sensory cells suffer from various acute or chronic injuries, such as excessive sound stimulation, ototoxic drugs, and age-related ...
Yu-Chen Liu, Kai Xu
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Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss
Frontiers in Pharmacology, 2014 Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
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Assessment of drug permeability through an ex vivo porcine round window membrane model
iScience, 2023 Summary: Delivery of pharmaceutical therapeutics to the inner ear to treat and prevent hearing loss is challenging. Systemic delivery is not effective as only a small fraction of the therapeutic agent reaches the inner ear.
Adele Moatti +9 more
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Application of Nanomedicine in Inner Ear Diseases
Frontiers in Bioengineering and Biotechnology, 2022 The treatment of inner ear disorders always remains a challenge for researchers. The presence of various physiological barriers, primarily the blood–labyrinth barrier (BLB), limits the accessibility of the inner ear and hinders the efficacy of various ...
Qianyu Lin +12 more
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Vestibular schwannoma and ipsilateral endolymphatic hydrops: an unusual association [PDF]
, 2017 Vestibular schwannoma and endolymphatic hydrops are two conditions that may present with similar audio-vestibular symptoms. The association of the two in the same patient represents an unusual nding that may lead clinicians to errors and delays in ...
ALTISSIMI, Giancarlo +8 more
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Systemic lupus erythematosus and hearing disorders: literature review and meta-analysis of clinical and temporal bone findings [PDF]
, 2017 Objective: This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE).
DI STADIO, Arianna, Ralli, Massimo
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Arthritis Care &Research, Accepted Article.Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla +13 more
wiley +1 more source
Determining the Location of GABA Receptor mRNA Transcripts in \u3cem\u3eDanio rerio\u3c/em\u3e [PDF]
, 2018 -aminobutyric acid (GABA) is a neurotransmitter that has been shown to be present in the inner ear. GABA binds to two classes of GABA receptors (GABARs): GABAARs are pentameric ion channels (isoforms include: 1-6, β 1-3, 1-3, 1-3, , , and ); GABABRs ...
O\u27Keefe, Jack
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Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium. [PDF]
, 2015 The endolymphatic sac (ES) is a cystic organ that is a part of the inner ear and is connected to the cochlea and vestibule. The ES is thought to be involved in inner ear ion homeostasis and fluid volume regulation for the maintenance of hearing and ...
Choi, Jae Young +8 more
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Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source