Results 41 to 50 of about 451,488 (358)

Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium

open access: yesJournal of Nanobiotechnology, 2010
Background Treatment of inner ear diseases remains a problem because of limited passage through the blood-inner ear barriers and lack of control with the delivery of treatment agents by intravenous or oral administration. As a minimally-invasive approach,
Kinnunen Paavo KJ   +6 more
doaj   +1 more source

Autophagy in the Vertebrate Inner Ear [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2017
Autophagy is a conserved catabolic process that results in the lysosomal degradation of cell components. During development, autophagy is associated with tissue and organ remodeling, and under physiological conditions it is tightly regulated as it plays a housekeeping role in removing misfolded proteins and damaged organelles.
Marta Magariños   +9 more
openaire   +6 more sources

Gene Delivery into the Inner Ear and Its Clinical Implications for Hearing and Balance

open access: yesMolecules, 2018
The inner ear contains many types of cell, including sensory hair cells and neurons. If these cells are damaged, they do not regenerate. Inner ear disorders have various etiologies.
Sho Kanzaki
doaj   +1 more source

Functional anatomy of the middle and inner ears of the red fox, in comparison to domestic dogs and cats

open access: yes, 2020
Anatomical middle and inner ear parameters are often used to predict hearing sensitivities of mammalian species. Given that ear morphology is substantially affected both by phylogeny and body size, it is interesting to consider whether the relatively ...
Burda, H., Malkemper, E., Mason, M.
core   +1 more source

Inner ear tissue preservation by rapid freezing: improving fixation by high-pressure freezing and hybrid methods [PDF]

open access: yes, 2014
In the preservation of tissues in as ‘close to life’ state as possible, rapid freeze fixation has many benefits over conventional chemical fixation. One technique by which rapid freeze-fixation can be achieved, high pressure freezing (HPF), has been ...
A. Bullen   +47 more
core   +1 more source

Multimodal Atlas of the Murine Inner Ear: From Embryo to Adult

open access: yesFrontiers in Neurology, 2021
The inner ear is a complex organ housed within the petrous bone of the skull. Its intimate relationship with the brain enables the transmission of auditory and vestibular signals via cranial nerves.
Jean-Paul Bryant   +15 more
doaj   +1 more source

Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies

open access: yesBalkan Medical Journal, 2019
Inner ear anomalies diagnosed using a radiological study are detected in almost 30% of cases with congenital or prelingual-onset sensorineural hearing loss.
Emre Ocak, Duygu Duman, Mustafa Tekin
doaj   +1 more source

WNT Activation and TGFβ-Smad Inhibition Potentiate Stemness of Mammalian Auditory Neuroprogenitors for High-Throughput Generation of Functional Auditory Neurons In Vitro

open access: yesCells, 2022
Hearing loss affects over 460 million people worldwide and is a major socioeconomic burden. Both genetic and environmental factors (i.e., noise overexposure, ototoxic drug treatment and ageing), promote the irreversible degeneration of cochlear hair ...
Francis Rousset   +6 more
doaj   +1 more source

Molding the asymmetry of localized frequency-locking waves by a generalized forcing and implications to the inner ear [PDF]

open access: yesPhys. Rev. E 98, 020202 (2018), 2018
Frequency locking to an external forcing frequency is a {well} known phenomenon. In the auditory system, it results in a localized traveling wave, the shape of which is essential for efficient discrimination between incoming frequencies. An amplitude equation approach is used to show that the shape of the localized traveling wave depends crucially on ...
arxiv   +1 more source

Systemic lupus erythematosus and hearing disorders: literature review and meta-analysis of clinical and temporal bone findings [PDF]

open access: yes, 2017
Objective: This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE).
DI STADIO, Arianna, Ralli, Massimo
core   +1 more source

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