Results 41 to 50 of about 1,559,915 (394)
, 2020 Anatomical middle and inner ear parameters are often used to predict hearing sensitivities of mammalian species. Given that ear morphology is substantially affected both by phylogeny and body size, it is interesting to consider whether the relatively ...
Burda, H., Malkemper, E., Mason, M.
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Inner ear morphology in the Atlantic molly Poecilia mexicana [PDF]
, 2011 Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Hess, Martin +2 more
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Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration
Nanoscale Research Letters, 2017 Liposome nanocarriers (LPNs) are potentially the future of inner ear therapy due to their high drug loading capacity and efficient uptake in the inner ear after a minimally invasive intratympanic administration.
Jing Zou +4 more
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AAV2.7m8 is a powerful viral vector for inner ear gene therapy
Nature Communications, 2019 Adeno-associated virus (AAV) has been successfully used to deliver gene therapy to improve auditory function in mouse models of hereditary hearing loss.
Kevin T. Isgrig +5 more
semanticscholar +1 more source
Journal of Nanobiotechnology, 2010 Background Treatment of inner ear diseases remains a problem because of limited passage through the blood-inner ear barriers and lack of control with the delivery of treatment agents by intravenous or oral administration. As a minimally-invasive approach,
Kinnunen Paavo KJ +6 more
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Nanoparticles in Inner Ear Diseases
National Board of Examinations Journal of Medical Sciences, 2023 Nanoparticles are novel discoveries which hold a promising role for delivering medications into the inner ear in the future. Nanoparticles are formed by the preparation of different biomaterials.
Soumick Ranjan Sahoo
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Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders
Nature Communications, 2019 Fifty percent of inner ear disorders are caused by genetic mutations. To develop treatments for genetic inner ear disorders, we designed gene replacement therapies using synthetic adeno-associated viral vectors to deliver the coding sequence for ...
Carl Nist-Lund +11 more
semanticscholar +1 more source
Asymmetrically severe internal auditory canal hypoplasia: A case report. [PDF]
, 2020 We present a case of an otherwise healthy 20-month-old with congenital sensorineural hearing loss. CT and MR imaging demonstrated bilateral asymmetrically severe hypoplasia of the internal auditory canals and vestibulocochlear nerves.
Djalilian, Hamid R +6 more
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Autophagy in the Vertebrate Inner Ear [PDF]
Frontiers in Cell and Developmental Biology, 2017 Autophagy is a conserved catabolic process that results in the lysosomal degradation of cell components. During development, autophagy is associated with tissue and organ remodeling, and under physiological conditions it is tightly regulated as it plays a housekeeping role in removing misfolded proteins and damaged organelles.
Marta Magariños +9 more
openaire +6 more sources
Gene Delivery into the Inner Ear and Its Clinical Implications for Hearing and Balance
Molecules, 2018 The inner ear contains many types of cell, including sensory hair cells and neurons. If these cells are damaged, they do not regenerate. Inner ear disorders have various etiologies.
Sho Kanzaki
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