Results 51 to 60 of about 453,737 (312)

Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss

Frontiers in Pharmacology, 2014
Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
doaj   +1 more source

Multifrequency Forcing of a Hopf Oscillator Model of the Inner Ear [PDF]

, 2007
In response to a sound stimulus, the inner ear emits sounds called otoacoustic emissions. While the exact mechanism for the production of otoacoustic emissions is not known, active motion of individual hair cells is thought to play a role. Two possible sources for otoacoustic emissions, both localized within individual hair cells, include somatic ...
arxiv   +1 more source

The avian tectorial membrane: Why is it tapered? [PDF]

AIP Conf. Proc. 1703, 080005 (2015), 2015
While the mammalian- and the avian inner ears have well defined tonotopic organizations as well as hair cells specialized for motile and sensing roles, the structural organization of the avian ear is different from its mammalian cochlear counterpart. Presumably this difference stems from the difference in the way motile hair cells function.
arxiv   +1 more source

Application of Nanomedicine in Inner Ear Diseases

Frontiers in Bioengineering and Biotechnology, 2022
The treatment of inner ear disorders always remains a challenge for researchers. The presence of various physiological barriers, primarily the blood–labyrinth barrier (BLB), limits the accessibility of the inner ear and hinders the efficacy of various ...
Qianyu Lin, Qianyu Lin, Qiong Guo, Qiong Guo, Mingchao Zhu, Juanli Zhang, Bei Chen, Tingting Wu, Tingting Wu, Wei Jiang, Wei Jiang, Wenxue Tang, Wenxue Tang   +12 more
doaj   +1 more source

Round window membrane and delivery of biologically active agents into the cochlea [PDF]

, 2010
Establishing efficient methods for local administration of drugs to the inner ear has great clinical relevance for the management of inner ear disorders. However, the administration route remains a critical issue.
Saber, Amanj K.
core   +1 more source

Advances in Hybrid Icing and Frosting Protection Strategies for Optics, Lens, and Photonics in Cold Environments Using Thin‐Film Acoustic Waves

Advanced Engineering Materials, EarlyView.
This article provides a comprehensive overview of fundamentals and recent advances of transparent thin‐film surface acoustic wave technologies on glass substrates for monitoring and prevention/elimination of fog, ice, and frost. Fogging, icing, or frosting on optical lenses, optics/photonics, windshields, vehicle/airplane windows, and solar panel ...
Hui Ling Ong, Zhangbin Ji, Luke Haworth, Yihao Guo, Jaime del Moral, Stefan Jacob, Ana Borras, Agustin R. Gonzalez‐Elipe, Jikai Zhang, Jian Zhou, Glen McHale, Yong‐Qing Fu   +11 more
wiley   +1 more source

Determining the Location of GABA Receptor mRNA Transcripts in \u3cem\u3eDanio rerio\u3c/em\u3e [PDF]

, 2018
-aminobutyric acid (GABA) is a neurotransmitter that has been shown to be present in the inner ear. GABA binds to two classes of GABA receptors (GABARs): GABAARs are pentameric ion channels (isoforms include: 1-6, β 1-3, 1-3, 1-3, , , and ); GABABRs ...
O\u27Keefe, Jack
core   +1 more source

Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression [PDF]

, 2015
In vertebrates, the inner ear arises from the otic placode, a thickened swathe of ectoderm that invaginates to form the otic vesicle. We report that histone demethylase KDM4B is dynamically expressed during early stages of chick inner ear formation.
Acloque, Ailín L. Buzzi, Alvarez, Baker, Barald, Barembaum, Beyer, Bokoch, Borges, Bradnam, Brown, Brown, Campanero, Chen, Cheng, Christophorou, Cobos, Couture, Deitcher, Driver, Dutton, Emmett, Fodor, Gerchman, Govek, Groves, Hans, Hofmann, Kalari, Kawazu, Lee, Li, Liu, Luo, Majewski, Marianne E. Bronner, Martin, Moro-Balbás, Neves, Pablo H. Strobl-Mazzulla, Park, Represa, Rosa A. Uribe, Sai, Sai, Siegfried, Sims, Stevens, Streit, Strobl-Mazzulla, Tan, Theveneau, Van Kerschaver, Visconti   +53 more
core   +3 more sources

Engineered Peptides‐Based Hybrid‐Nested Microneedle Effectively Treat Biofilm‐Infected Diabetic Wounds

Advanced Functional Materials, EarlyView.
A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi, S. M. Shatil Shahriar, Yiran Tian, Farzad Hayati, Yajuan Su, Feng Zhang, Navatha Shree Sharma, Guangshun Wang, Shannon L. Wong, Zheng Yan, Guoliang Huang, Jingwei Xie   +11 more
wiley   +1 more source

Direct SARS-CoV-2 infection of the human inner ear may underlie COVID-19-associated audiovestibular dysfunction

Communications Medicine, 2021
Plain language summary Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the novel coronavirus SARS-CoV-2. A growing number of sensory symptoms have been linked to this illness.
Minjin Jeong, Karen E. Ocwieja, Dongjun Han, P. Ashley Wackym, Yichen Zhang, Alyssa Brown, Cynthia Moncada, Andrea Vambutas, Theodore Kanne, Rachel Crain, Noah Siegel, Valerie Leger, Felipe Santos, D. Bradley Welling, Lee Gehrke, Konstantina M. Stankovic   +15 more
doaj   +1 more source