Results 71 to 80 of about 453,570 (346)

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

Advanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei, Luping Wang, Haitong Jing, Xian Qin, Jiong‐Wei Wang, Xiaogang Liu   +5 more
wiley   +1 more source

Roles of supporting cells in the maintenance and regeneration of the damaged inner ear: A literature review

Journal of Otology
The inner ear sensory epithelium consists of two major types of cells: hair cells (HCs) and supporting cells (SCs). Critical functions of HCs in the perception of mechanical stimulation and mechanosensory transduction have long been elucidated.
Jing-Ying Guo, Jun-Yi Xu, Shu-Sheng Gong, Guo-Peng Wang   +3 more
doaj   +1 more source

Role of Dach1 revealed using a novel inner ear-specific Dach1-knockdown mouse model

Biology Open, 2019
The Dach1 gene is expressed in the inner ear of normal mouse embryos in the area that differentiates into the cochlear stria vascularis (SV). We hypothesised that Dach1 downregulation in the inner ear would lead to SV dysplasia.
Toru Miwa, Ryosei Minoda, Yoshihide Ishikawa, Tomohito Kajii, Yorihisa Orita, Takahiro Ohyama   +5 more
doaj   +1 more source

The Active Traveling Wave in the Cochlea [PDF]

, 2003
A sound stimulus entering the inner ear excites a deformation of the basilar membrane which travels along the cochlea towards the apex. It is well established that this wave-like disturbance is amplified by an active system.
D. D. Greenwood, D. T. Kemp, Frank Jülicher, G. von Békésy, G. Zweig, G. Zweig, H. Duifuis, J. Ashmore, J. Lighthill, J. Zwislocki, L. Robles, P. J. Kolston, T. Gold, Thomas Duke, W. E. Brownell, W. S. Rhode   +15 more
core   +2 more sources

Waveguide Photoactuators: Materials, Fabrication, and Applications

Advanced Robotics Research, EarlyView.
Waveguide photoactuators convert guided light into mechanical motion. Their tethered‐flexible design enables minimally invasive surgery and confined‐space robotics. This review aims to guide materials selection, device design, and system integration, accelerating the transition of waveguide photoactuators from laboratory prototypes to versatile ...
Minjie Xi, Hemin Pan, Yang Zong, Yongfeng Mei, Jizhai Cui   +4 more
wiley   +1 more source

Inner ear organoids: Recent progress and potential applications

Fundamental Research
The inner ear is one of the most complicated structures that harbor organs for the perception of sound and balance, which is deep in the temporal bone and challenging to operate.
Yiyun Lou, Yaoqian Liu, Mingxuan Wu, Gaogan Jia, Mingyu Xia, Wenyan Li   +5 more
doaj   +1 more source

Inner Ear Therapeutics: An Overview of Middle Ear Delivery

Frontiers in Cellular Neuroscience, 2019
There are a variety of methods to access the inner ear and many of these methods depend on utilizing the middle ear as a portal. In this approach the middle ear can be used as a passive receptacle, as part of an active drug delivery system, or simply as ...
Jaimin Patel, Mikhaylo Szczupak, Suhrud Rajguru, Suhrud Rajguru, Carey Balaban, Michael E. Hoffer, Michael E. Hoffer   +6 more
doaj   +1 more source

Interactions of Interaural Time and Level Differences in Spatial Hearing with Cochlear Implants

Advanced Science, EarlyView.
Differences in timing (ΔT) are weighted heavily compared to differences in loudness (ΔL) in binaural hearing with cochlear implants. Abstract Normally hearing humans can localize sound sources quite accurately, with minimum audible angles as small as 1°. To achieve this, these auditory pathways combine information from multiple acoustic cues, including
Sarah Buchholz, Susan Arndt, Jan W. H. Schnupp, Nicole Rosskothen‐Kuhl   +3 more
wiley   +1 more source

Sufu and Gli3 repressor mediate the temporal basal-to-apical progression of hair cell differentiation in mammalian cochleae [PDF]

, 2014
Poster presentation - Theme 3: Development & stem cellsThe Sonic Hedgehog pathway plays important roles in mammalian inner ear development. Mutations of Shh, Smo and Gli3 lead to severe defects in mouse inner ear morphogenesis.
Hui, CC, Liu, Y, Sham, MH, Wang, B, Wong, EYM   +4 more
core  

Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid [PDF]

, 2016
With their essential role in inner-ear function, stereocilia of sensory hair cells demonstrate the importance of cellular actin protrusions. Actin packing in stereocilia is mediated by crosslinkers of the plastin, fascin, and espin families.
Avenarius, Burkard, Chhabra, Claessens, Cox, Cox, Crawley, DeRosier, DeRosier, DeRosier, DeRosier, Drummond, Dumont, Ebrahim, Egelman, Eng, Erde, Francis, Gallien, Gardel, Gillespie, Grimm-Günter, Grüneberg, Gupton, Gustafsson, Hudspeth, Hwang, Jansen, Jones, Jones, Jones, Krey, Krey, Li, Merritt, Michelot, Mogensen, Perrin, Perrin, Purdy, Revenu, Rzadzinska, Salles, Sekerková, Shepherd, Shevchenko, Shin, Shin, Shin, Taylor, Tilney, Tilney, Tilney, Tilney, Tilney, Vignjevic, Volkmann, Waingeh, Wilmarth, Zheng   +59 more
core   +2 more sources