Results 71 to 80 of about 447,391 (302)

Inner Ear Therapeutics: An Overview of Middle Ear Delivery

Frontiers in Cellular Neuroscience, 2019
There are a variety of methods to access the inner ear and many of these methods depend on utilizing the middle ear as a portal. In this approach the middle ear can be used as a passive receptacle, as part of an active drug delivery system, or simply as ...
Jaimin Patel, Mikhaylo Szczupak, Suhrud Rajguru, Suhrud Rajguru, Carey Balaban, Michael E. Hoffer, Michael E. Hoffer   +6 more
doaj   +1 more source

Sufu and Gli3 repressor mediate the temporal basal-to-apical progression of hair cell differentiation in mammalian cochleae [PDF]

, 2014
Poster presentation - Theme 3: Development & stem cellsThe Sonic Hedgehog pathway plays important roles in mammalian inner ear development. Mutations of Shh, Smo and Gli3 lead to severe defects in mouse inner ear morphogenesis.
Hui, CC, Liu, Y, Sham, MH, Wang, B, Wong, EYM   +4 more
core  

Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid [PDF]

, 2016
With their essential role in inner-ear function, stereocilia of sensory hair cells demonstrate the importance of cellular actin protrusions. Actin packing in stereocilia is mediated by crosslinkers of the plastin, fascin, and espin families.
Avenarius, Burkard, Chhabra, Claessens, Cox, Cox, Crawley, DeRosier, DeRosier, DeRosier, DeRosier, Drummond, Dumont, Ebrahim, Egelman, Eng, Erde, Francis, Gallien, Gardel, Gillespie, Grimm-Günter, Grüneberg, Gupton, Gustafsson, Hudspeth, Hwang, Jansen, Jones, Jones, Jones, Krey, Krey, Li, Merritt, Michelot, Mogensen, Perrin, Perrin, Purdy, Revenu, Rzadzinska, Salles, Sekerková, Shepherd, Shevchenko, Shin, Shin, Shin, Taylor, Tilney, Tilney, Tilney, Tilney, Tilney, Vignjevic, Volkmann, Waingeh, Wilmarth, Zheng   +59 more
core   +2 more sources

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Inner-ear abnormalities and their functional consequences in Belgian Waterslager canaries (Serinus canarius) [PDF]

, 1994
Recent reports of elevated auditory thresholds in canaries of the Belgian Waterslager strain have shown that this strain has an inherited auditory deficit in which absolute auditory thresholds at high frequencies (i.e. above 2.0 kHz) are as much as 40 dB
Brown, Cleveland, Corwin, Cotanche, Cotanche, Cotanche, Cousillas, Dooling, Dooling, Fischer, Geoffrey A. Manley, Girod, Girod, Gleich, Gleich, Gleich, Gleich, Gleich, Gummer, Guttinger, Hashino, Hashino, Köppl, Manley, Manley, Manley, Marler, Nottebohm, Okanoya, Okanoya, Okanoya, Okanoya, Okanoya, Otto Gleich, Patuzzi, Pickles, Robert J. Dooling, Saunders, Steel, Steel, Stresemann, Tilney, Waser   +42 more
core   +1 more source

A novel cochlear measurement that predicts inner-ear malformation [PDF]

, 2021
Tawfiq Khurayzi, Fida Almuhawas, Abdulrahman Alsanosi, Yassin Abdelsamad, Úna Doyle, Anandhan Dhanasingh   +5 more
openalex   +1 more source

Scalable Etch‐Free Transfer of Low‐Dimensional Materials From Metal Films to Diverse Substrates

Advanced Materials Interfaces, EarlyView.
A scalable, etch‐free transfer method for low‐dimensional materials is presented, utilizing a low‐melting‐point metal as a reusable support. This technique enables gentle wafer‐scale electrochemical delamination from mechanically fragile metal thin‐film substrates and supports integration into device architectures.
Kentaro Yumigeta, Muhammed Yusufoglu, Mamun Sarker, Rishi Raj, Franco Daluisio, Richard Holloway, Howard Yawit, Thomas Sweepe, Julian Battaglia, Shelby Janssen, Alex C. Welch, Paul DiPasquale, K. Andre Mkhoyan, Alexander Sinitskii, Zafer Mutlu   +14 more
wiley   +1 more source

Connexins and gap junctions in the inner ear - it's not just about K(+) recycling [PDF]

, 2014
Normal development, function and repair of the sensory epithelia in the inner ear are all dependent on gap junctional intercellular communication.
Forge, A, Jagger, DJ
core   +2 more sources

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa, Alessio Esposito, Giovanni Vozzi, Riccardo Gottardi, Carmelo De Maria   +4 more
wiley   +1 more source

Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors

Nature Communications, 2018
Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here the authors examine human inner ear development by studying key developmental markers and describe organoid cultures from human ...
Marta Roccio, Michael Perny, Megan Ealy, Hans Ruedi Widmer, Stefan Heller, Pascal Senn   +5 more
doaj   +1 more source